Hydroxypinacolone Retinoate (HPR) is a next-generation retinoid widely used in advanced skincare formulations for its anti-aging and skin-renewing properties. It effectively promotes collagen synthesis, helping to reduce the appearance of wrinkles and fine lines, while also accelerating keratinocyte metabolism and inhibiting melanin production for a more even skin tone.
This active ingredient is supplied as a yellow crystalline powder and is soluble in alcohol, making it easy to incorporate into serums, creams, and other alcohol-based skincare products. With a recommended usage of 0.01–0.3%, it delivers potent efficacy at a low dosage, providing both visible results and formulation stability.
Compared with traditional retinol and retinal, Hydroxypinacolone Retinoate (HPR) works directly without conversion, offering faster visible results with significantly lower irritation.
While retinol must convert into retinal and then retinoic acid in the skin, HPR binds directly to retinoid receptors, providing high efficacy at low dosages. It delivers smoother texture and even tone benefits with less stinging, redness, or dryness—making it ideal for sensitive or retinoid-intolerant skin.
ZLEY®HPR
| INCI: | Hydroxypinacolone Retinoate |
| Properties: | Promotes skin collagen synthesis and reduces wrinkles and fine lines. A great recommendation for accelerating keratinocyte metabolism and inhibiting melanin production. |
| Appearance: | Yellow crystalline powder |
| Recommended dosage: | 0.01-0.3% |
| Solubility: | Soluble in alcohol |
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