Stephania Tetrandra Extract in ZLEY® PE401-PHEACNE
A soothing ingredient is useful to a formulator only when its composition and processing guidance are clear. ZLEY® PE401-PHEACNE is a supplied blend of Stephania Tetrandra Extract, butylene glycol and water. The extract is one component of the blend, rather than the whole material. Its published technical data sheet (TDS) lists the extract at 0.08–0.15% of the supplied ingredient.
What is in the supplied blend?
Der ZLEY® PE401-PHEACNE TDS gives the composition below. The ranges describe the supplied raw material; check the current certificate of analysis (COA) for the batch you buy.
| Component | Published TDS range |
|---|---|
| Stephania Tetrandra Extract (CAS 223748-82-1) | 0.08–0.15% |
| Butylene Glycol (CAS 107-88-0) | 49.9–69.9% |
| Water (CAS 7732-18-5) | 30.0–50.0% |
The TDS describes a colorless liquid with a characteristic odor and specifies quality checks including microbial counts and selected heavy metals. Those specification figures should be confirmed against the latest documents for the intended market.
How should formulators use it?
The supplier suggests 0.5–5% of the supplied blend and says it is water-soluble. Its processing note calls for adding the material at roughly 50°C and mixing evenly. This is supplier guidance, not a universal regulatory maximum or proof that every finished formula will remain stable. Verify color, odor, stability and packaging in the actual formula. See the ZLEY® PE401-PHEACNE product page for the current product overview and document downloads.
What can the evidence support?
ZLEY positions this ingredient for skin-conditioning and soothing formulas. The TDS describes possible anti-inflammatory and skin-comfort applications, but it does not provide a controlled human clinical study establishing that this blend prevents post-inflammatory hyperpigmentation, repairs the skin’s immune system or treats allergies. Such outcomes should not be promised for a finished cosmetic without suitable product-specific evidence and regulatory review.
Read the supplier safety data sheet alongside the TDS. It flags irritation hazards for handling the concentrated raw material. Finished-product tolerance, especially for a product marketed to sensitive-skin users, must be assessed separately.
Buyer checklist
Before specifying the ingredient, ask for the current COA, TDS and SDS. Check extract content, solvent composition, microbial limits and target-market requirements. Trial the suggested starting level in your formula and record stability and compatibility results. These checks make a more useful purchasing decision than an unqualified “anti-allergy” claim.