A Lipid-Chain Salicylic Acid Derivative for Gentle, Effective Exfoliation

ZLEY® Capryloyl Salicylic Acid (CAS 78418-01-6):

A Lipid-Chain Salicylic Acid Derivative for Gentle, Effective Exfoliation

Product Overview

Capryloyl Salicylic Acid is used in cosmetics as a skin conditioning agent, spot‑correcting agent, and preservative. It is a salicylic acid derivative with an added lipid chain. Compared to salicylic acid and conventional AHAs (alpha‑hydroxy acids), it penetrates the stratum corneum more easily and gradually loosens intercellular junctions, enabling more effective microexfoliation. This results in smoother, more refined skin with visibly reduced imperfections.

Salicylic acid is a key component in aspirin synthesis. Studies have shown that oral intake of salicylic acid can have effects similar to taking aspirin orally, potentially leading to fetal malformations, increased miscarriage risk, and other pregnancy complications. However, there is no scientific evidence that topical application of salicylic acid affects pregnancy. For safety reasons, it is recommended that pregnant and breastfeeding women use products containing this ingredient with caution.

ZLEY® is a professional supplier of Capryloyl Salicylic Acid (CAS 78418-01-6), providing stable quality, technical support, and global delivery covering over 60 countries.

ZLEY® Capryloyl Salicylic Acid Product Information

Is ZLEY® Capryloyl Salicylic Acid Safe?

Yes. According to the safety assessment by the U.S. Cosmetic Ingredient Review (CIR) Expert Panel, this ingredient is considered safe at concentrations up to 0.5% in leave-on products and up to 0.4% in rinse-off products. Under normal, reasonable, and foreseeable conditions of use, it does not pose a risk to human health.

Product Applications

Capryloyl Salicylic Acid retains the keratolytic (exfoliating) efficacy of salicylic acid while offering enhanced affinity for skin cells, allowing it to penetrate the stratum corneum more effectively. It serves as a topical ingredient for anti-aging and blackhead/comedone treatment in cosmetic formulations.

Why Source ZLEY® Capryloyl Salicylic Acid from ZLEY®?

With over 20 years of dedicated experience, ZLEY® has evolved into a modern enterprise integrating research, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.

Email: [email protected]

What Technical Support Can You Expect?

As a specialized supplier, ZLEY® offers value beyond the product itself:

• Formulation Support: Basic formulation recommendations, combination suggestions, and processing guidance
• Regulatory Consulting: Assistance with interpreting compliance requirements for target markets
• Quality Assurance: Consistent quality, competitive pricing, and reliable global logistics
• Market Intelligence: Latest market trends and ingredient application insights

ZLEY® Capryloyl Salicylic Acid – Frequently Asked Questions (FAQ)

Q1: What is Capryloyl Salicylic Acid, and how is it different from regular Salicylic Acid?

A: Capryloyl Salicylic Acid (INCI: Capryloyl Salicylic Acid, CAS: 78418-01-6) is a salicylic acid derivative with an added lipid (capryloyl) chain. Compared to conventional salicylic acid and common AHAs, its key advantage is enhanced penetration into the stratum corneum. It gradually loosens intercellular junctions, enabling more effective microexfoliation. Its stronger affinity for skin cells makes it more gentle and targeted, resulting in smoother, more refined skin with visibly reduced imperfections.

Q2: What are the key benefits of ZLEY® Capryloyl Salicylic Acid?

A: It is primarily used as a skin conditioning agent and offers a wide range of benefits:

• Skin Refinement & Anti-Aging: Gently exfoliates dead skin cells, promotes cell renewal, helps reduce fine lines and wrinkles, and improves skin tone and radiance.
• Acne & Sebum Control: Effective in treating acne, comedones (blackheads/whiteheads), and can work synergistically with other ingredients for oil control.
• Brightening: Helps fade hyperpigmentation and improve dullness by accelerating keratinocyte turnover.

Q3: Is ZLEY® Capryloyl Salicylic Acid safe? Can it be used during pregnancy?

A: According to the U.S. Cosmetic Ingredient Review (CIR) Expert Panel, Capryloyl Salicylic Acid is safe at concentrations up to 0.5% in leave‑on products and up to 0.4% in rinse‑off products. However, it is a potent active ingredient and may not be suitable for everyone. Regarding use during pregnancy and breastfeeding, while there is no definitive evidence that topical application causes fetal harm, salicylate derivatives do raise safety concerns. Medical experts generally advise caution or avoidance to prevent potential skin irritation or systemic absorption concerns.

Q4: What are the formulation and processing guidelines?

A:

• Solubilization: Since it is insoluble in water, pre-dissolve in ethanol, butylene glycol, or other organic solvents before adding to the aqueous phase.
• Temperature: Avoid prolonged heating at high temperatures (melting point ≈ 115°C). It is recommended to add during the cooling phase (around 50-60°C after emulsification).
• Compatibility: Compatible with most cosmetic ingredients. Soothing agents (e.g., bisabolol) can be added to reduce potential irritation.
• Storage: Store in a cool, dry place in tightly sealed containers, protected from light.