Hydroxypinacolone Retinoate (HPR) is a retinoic-acid ester used in professional well-aging and skin-renewal formulation development. ZLEY®HPR is supplied as a yellow crystalline powder; the published TDS specifies NLT 99.0% purity by HPLC and a suggested use level of 0.01–0.3%.
The SDS lists ready solubility in selected carrier solvents including 1,2-pentanediol, 1,2-hexanediol, diacetone alcohol, ethoxydiglycol and dimethyl isosorbide. The TDS recommends oil-based or structured emulsion routes and does not recommend a pure-water system or a dilute emulsion with a viscosity figure below 1,500 (measurement unit and method are not stated in the TDS).
Protect the material and finished formula from avoidable light and oxygen exposure. Confirm the current TDS/SDS, target-market assessment, compatibility, stability and packaging before commercial release.
Hydroxypinacolone Retinoate — ZLEY®HPR
| INCI: | Hydroxypinacolone Retinoate |
| CAS: | 893412-73-2 |
| Content/Purity: | NLT 99.0% by HPLC |
| Appearance: | Yellow crystalline powder |
| Recommended dosage: | 0.01–0.3% |
| Solubility: | Soluble in selected glycols and carrier solvents; see the current TDS/SDS |
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ZLEY®HPR at a glance
ZLEY®HPR is a high-purity Hydroxypinacolone Retinoate grade for retinoid skincare development. Its published TDS specifies NLT 99.0% HPLC purity and a suggested use level of 0.01–0.3%.
- INCI
- Hydroxypinacolone Retinoate
- CAS
- 893412-73-2
- Content / purity
- NLT 99.0% by HPLC
- Appearance
- Yellow crystalline powder
- Recommended dosage
- 0.01–0.3%
- Solubility
- Easily soluble in 1,2-pentanediol, 1,2-hexanediol, diacetone alcohol, ethoxydiglycol and dimethyl isosorbide
Formulation and purchasing details View 10 additional specifications
- Addition phase
- Use a validated carrier-solvent/oil-phase route; the TDS does not recommend pure-water systems or dilute emulsions (viscosity below 1,500; measurement unit and method are not stated)
- Processing temperature
- Not stated in the published TDS; minimize heat and confirm the grade-specific process before scale-up
- pH
- Not specified for the supplied powder
- Stability
- Use antioxidants and chelating support where appropriate; validate light, oxygen, compatibility and packaging stability
- Storage
- Store sealed in a cool, dry, well-ventilated place away from incompatible materials and food
- Shelf life
- 2 years under the TDS storage conditions
- Applications
- Oil-based systems, water-in-oil, water-in-silicone and silicone-in-water systems; well-aging and skin-renewal formulations
- Packaging
- 1 kg aluminum film bag lined with polyethylene, according to the published TDS
- MOQ
- Available on request; confirm pack multiple, lead time and destination with ZLEY sales
- TDS / SDS / COA
- TDS linked; SDS linked; Batch-specific COA available on request
Values marked for confirmation are intentionally not estimated. Request the current grade-specific TDS/SDS and batch COA before scale-up or purchase.
Technical documents
Product FAQ
What is ZLEY®HPR?
ZLEY®HPR is a high-purity Hydroxypinacolone Retinoate grade for retinoid skincare development. Its published TDS specifies NLT 99.0% HPLC purity and a suggested use level of 0.01–0.3%. The declared INCI is: Hydroxypinacolone Retinoate.
What is the recommended use level for ZLEY®HPR?
The published or currently recorded use level is 0.01–0.3%. Final use level must be checked against the current TDS, the complete formula, target-market rules and finished-product testing.
How should ZLEY®HPR be incorporated?
Solubility: Easily soluble in 1,2-pentanediol, 1,2-hexanediol, diacetone alcohol, ethoxydiglycol and dimethyl isosorbide. Addition phase: Use a validated carrier-solvent/oil-phase route; the TDS does not recommend pure-water systems or dilute emulsions (viscosity below 1,500; measurement unit and method are not stated). Processing temperature: Not stated in the published TDS; minimize heat and confirm the grade-specific process before scale-up.
Which technical and purchasing documents are available?
TDS is linked on this page; SDS is linked on this page; request the batch-specific COA. Packaging and MOQ are order-specific and should be confirmed with ZLEY sales before purchase.
Can ZLEY HPR powder be used in a pure-water serum?
The published TDS does not recommend this grade for pure-water systems or dilute emulsions. Select an appropriate carrier and formulation architecture with technical support, then validate compatibility and stability.
What pH and processing temperature should I use for HPR?
The linked powder TDS does not specify a universal finished-formula pH range or maximum addition temperature. Request grade-specific process guidance rather than inferring a limit from the melting point or another retinoid.
Technical review owner: ZLEY Group Technical Team Source review date: