24-Hour Sustained Efficacy – Gentle Penetration – Zero Burden on Skin

ZLEY® MecALA 10% (CAS 1077-28-7, 128446-33-3):

• 24-Hour Sustained Efficacy – Gentle Penetration – Zero Burden on Skin

Product Overview

ZLEY® MecALA 10% is an advanced skin conditioning agent featuring the naturally bioactive R‑form of alpha‑lipoic acid. As an essential coenzyme in human metabolism, R‑(+)-lipoic acid plays a key role in oxidative decarboxylation reactions. Its unique five‑membered dithiolane ring structure gives it high electron density, providing exceptional electrophilicity and free radical scavenging ability. Benefits include antioxidant protection, moisturization and repair, sebum control, anti‑aging effects, as well as recognized medical benefits such as combating fatty liver and reducing plasma cholesterol.

ZLEY® MecALA 10% utilizes supramolecular inclusion technology to overcome the poor water solubility and oxidative discoloration that have limited lipoic acid’s cosmetic applications. This technology significantly expands its formulation flexibility while preserving the superior bioactivity of the R‑form over the less active L‑form.

ZLEY® is a professional supplier of MecALA 10%, providing stable quality, technical support, and reliable global delivery to over 60 countries.

ZLEY® MecALA 10% Product Information

Is ZLEY® MecALA 10% Safe?

ZLEY® MecALA 10% is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following maximum concentrations:

• Leave-on products: ≤ 2.2%
• Rinse-off products: ≤ 0.1%

Key Technology – Supramolecular Inclusion

The supramolecular inclusion technology used in ZLEY® MecALA 10% delivers four critical advantages:

1. Enhanced stability – Protects R-(+)-lipoic acid from oxidative degradation and discoloration
2. Improved water solubility – Enables clear, stable aqueous formulations without organic solvents
3. 24-hour sustained efficacy – Controlled release provides prolonged antioxidant protection
4. Zero skin burden – Gentle delivery system minimizes irritation potential

Product Applications

ZLEY® MecALA 10% functions as a skin conditioning agent with potent antioxidant benefits. It is suitable for a wide range of product types:

• Water-based systems (toners, serums, essences)
• Emulsions (lotions, creams)
• Eye creams
• Children’s creams
• Sunscreen lotions
• Color cosmetics

Its excellent water solubility and mild profile make it particularly valuable for formulations targeting sensitive skin, daily antioxidant protection, and comprehensive anti-aging.

Why Source ZLEY® MecALA 10% from ZLEY®?

Through over 20 years of dedicated effort and pursuit of excellence, ZLEY® has evolved into a modern enterprise integrating research, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions. We strive to meet the diverse needs of our customers and ensure the delivery of superior products and service.

What Technical Support Can You Expect When Sourcing ZLEY® MecALA 10%?

As a specialized supplier, ZLEY® offers value that extends beyond the product itself:

Formulation Application Support: Basic formulation suggestions, combination recommendations, and processing guidance

Regulatory Consulting Services: Assistance with interpreting regulatory requirements for target markets

Quality and Supply Assurance: Consistent product quality, competitive pricing, and reliable global logistics delivery

Market Trend Information: Latest market dynamics and ingredient application trends

ZLEY® MecALA 10% – Frequently Asked Questions (FAQ)

Q1: What does “24-hour sustained efficacy” mean?

A: The supramolecular inclusion complex releases R‑(+)-lipoic acid gradually rather than all at once. This controlled release provides extended antioxidant protection for up to 24 hours after a single application. Sustained release also reduces the risk of irritation compared to the “burst release” of free lipoic acid.

Q2: Is ZLEY® MecALA 10% suitable for sensitive skin?

A: Yes. The gentle, controlled delivery system is specifically designed to provide a zero‑burden skin experience. Unlike free lipoic acid, which can cause tingling or irritation in some individuals, the encapsulated form releases the active ingredient gradually, minimizing any noticeable sensation while maintaining full efficacy. This makes it suitable for sensitive skin formulations and daily‑use products.

Q3: Does ZLEY® MecALA 10% have any odor issues?

A: The raw material has a characteristic odor typical of lipoic acid derivatives. However, at the recommended usage levels (0.2–2.2%), the odor is generally not detectable in finished formulations. For fragrance‑sensitive products, standard masking systems can be used.

Q4: How can I request samples, technical documentation, and pricing?

Please contact our export team via email:

Email: [email protected]

When inquiring, please include your company details, intended product application, and target market so we can provide the most relevant information for your specific needs.