ZLEY® HPR – Hydroxypinacolone Retinoate (CAS 893412-73-2):
The Next-Generation Retinoid – Direct-Acting HPR for Visible Anti-Aging with Zero Compromise on Gentleness

Product Overview
ZLEY® HPR (Hydroxypinacolone Retinoate) is an advanced skin conditioning agent used in cosmetics and skincare products. Its primary functions include promoting collagen synthesis in the dermis to improve existing wrinkles, preventing collagen degradation to avoid wrinkle formation, promoting normal differentiation of keratinocytes, accelerating keratinocyte turnover, and inhibiting melanin production in the skin.
ZLEY® is a professional supplier of Hydroxypinacolone Retinoate (CAS 893412-73-2), providing stable quality, technical support, and global delivery services covering over 60 countries.
ZLEY® HPR – Hydroxypinacolone Retinoate Product Information
| Parameter | Specification |
| INCI Name | Hydroxypinacolone Retinoate |
| CAS Number | 893412-73-2 |
| Appearance | Yellow powder |
| Recommended Usage | 0.051– 0.3% |
| Solubility | Oil-soluble; insoluble in water |
| Applications | Emulsions, creams, serums |
Is ZLEY® HPR – Hydroxypinacolone Retinoate Safe?
ZLEY® HPR is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions:
For full-body leave-on products: Maximum usage level of 0.3%
For eye area leave-on products: Maximum usage level of 0.2%
At these concentrations, it does not pose potential harm to human health.
Product Applications
Hydroxypinacolone Retinoate is a skin conditioning agent (as classified in Cosing) and a retinoid derivative. It offers the ability to regulate epidermal and stratum corneum metabolism, providing anti-aging benefits. It helps reduce sebum secretion, lighten epidermal pigmentation, and serves multiple functions including:
Preventing skin aging
Preventing acne
Brightening and reducing blemishes
While maintaining the powerful efficacy of traditional retinol, it significantly reduces irritation potential, making it ideal for anti-aging and acne recurrence prevention formulations.
Product Benefits
- Promotes Normal Keratinocyte Differentiation: Supports healthy skin cell development and turnover
- Prevents Dermal Collagen Degradation: Protects existing collagen to prevent wrinkle formation
- Stimulates Dermal Collagen Synthesis: Improves existing wrinkles through new collagen production
- Accelerates Keratinocyte Turnover & Inhibits Melanin Production: Supports skin renewal and even tone
Why Source ZLEY® HPR from ZLEY®?
Through over 20 years of dedicated effort and pursuit of excellence, ZLEY® has evolved into a modern enterprise integrating research, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions. We strive to meet the diverse needs of our customers and ensure the delivery of superior products and service.
Email: [email protected]
What Technical Support Can You Expect When Sourcing ZLEY® HPR?
As a specialized supplier, ZLEY® offers value that extends beyond the product itself:
- Formulation Application Support: Provides basic formulation suggestions, combination recommendations, and processing guidance
- Regulatory Consulting Services: Assists in interpreting regulatory requirements for target markets
- Quality and Supply Assurance: Ensures consistent product quality, competitive pricing, and reliable global logistics delivery
- Market Trend Information: Shares the latest market dynamics and ingredient application trends to support your product development strategy
ZLEY® HPR – Hydroxypinacolone Retinoate: Frequently Asked Questions (FAQ)
Q1: What is the recommended usage level for ZLEY® HPR?
A: The recommended usage range is 0.01 – 0.3% in finished cosmetic formulations.
Q2: Is ZLEY® HPR oil or water soluble?
A: It is oil-soluble and insoluble in water. It should be incorporated into the oil phase of formulations.
Q3: Is HPR effective for acne-prone skin?
A: Yes. By regulating keratinocyte differentiation and preventing the buildup of dead skin cells that clog pores, HPR is highly effective in helping to prevent acne and manage breakout-prone skin, making it suitable for anti-acne and acne recurrence prevention formulations.
Q4: How can I request samples, technical documentation, and pricing?
Please contact our export team via email:
Email: [email protected]
When inquiring, please include your company details, intended product application, and target market so we can provide the most relevant information for your specific needs.
