{"id":9641,"date":"2026-07-22T15:26:36","date_gmt":"2026-07-22T07:26:36","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9641"},"modified":"2026-07-22T15:26:36","modified_gmt":"2026-07-22T07:26:36","slug":"pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/ru\/pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent\/","title":{"rendered":"\u00a0\u0410\u043a\u0442\u0438\u0432\u043d\u044b\u0439 \u0438\u043d\u0433\u0440\u0435\u0434\u0438\u0435\u043d\u0442 \u0444\u0430\u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0430 \u2014 \u0443\u0441\u043f\u043e\u043a\u0430\u0438\u0432\u0430\u044e\u0449\u0435\u0435, \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0437\u0443\u0434\u043d\u043e\u0435 \u0438 \u0430\u043d\u0442\u0438\u043c\u0438\u043a\u0440\u043e\u0431\u043d\u043e\u0435 \u0441\u0440\u0435\u0434\u0441\u0442\u0432\u043e"},"content":{"rendered":"

ZLEY\u00ae PAE \u2013 Paeonol (CAS 552-41-0):<\/strong><\/strong><\/h2>\n\n\n\n

 \u0410\u043a\u0442\u0438\u0432\u043d\u044b\u0439 \u0438\u043d\u0433\u0440\u0435\u0434\u0438\u0435\u043d\u0442 \u0444\u0430\u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0430 \u2014 \u0443\u0441\u043f\u043e\u043a\u0430\u0438\u0432\u0430\u044e\u0449\u0435\u0435, \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0437\u0443\u0434\u043d\u043e\u0435 \u0438 \u0430\u043d\u0442\u0438\u043c\u0438\u043a\u0440\u043e\u0431\u043d\u043e\u0435 \u0441\u0440\u0435\u0434\u0441\u0442\u0432\u043e<\/strong><\/strong><\/h2>\n\n\n\n
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<\/figcaption><\/figure>\n\n\n\n

\u041e\u0431\u0437\u043e\u0440 \u043f\u0440\u043e\u0434\u0443\u043a\u0446\u0438\u0438<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE (Paeonol), also known as Peonol<\/strong> \u0438\u043b\u0438 2-hydroxy-4-methoxyacetophenone<\/strong>, is an active monomer compound extracted from the root bark of the peony plant (Paeonia suffruticosa) or the dried roots of Cynanchum paniculatum<\/a><\/a>. As a small-molecule phenolic compound, it offers a unique combination of antibacterial, anti-inflammatory, redness-reducing, and antioxidant benefits<\/a><\/a>.<\/p>\n\n\n\n

Paeonol has a long history of clinical use in China, with injectable formulations dating back to the 1970s. It is widely used in oral care, hair care, skincare, and cosmetic products<\/a><\/a>. Recent research has also highlighted its potential as an anti-acne adjuvant<\/strong>, with studies showing that it suppresses key inflammatory mediators, scavenges free radicals, and inhibits melanogenesis<\/a>.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Paeonol (CAS 552-41-0), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00ae PAE Product Information<\/strong><\/strong><\/h3>\n\n\n\n
\u041f\u0430\u0440\u0430\u043c\u0435\u0442\u0440<\/td>\u0422\u0435\u0445\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0438<\/td><\/tr>
\u041d\u0430\u0437\u0432\u0430\u043d\u0438\u0435 INCI<\/strong><\/td>\u041f\u0430\u0435\u043e\u043d\u043e\u043b<\/td><\/tr>
\u041d\u043e\u043c\u0435\u0440 CAS<\/strong><\/td>552-41-0<\/td><\/tr>
\u041f\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0435<\/strong><\/td>\u0411\u0435\u043b\u044b\u0439 \u0438\u043b\u0438 \u043f\u043e\u0447\u0442\u0438 \u0431\u0435\u043b\u044b\u0439 \u043a\u0440\u0438\u0441\u0442\u0430\u043b\u043b\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043f\u043e\u0440\u043e\u0448\u043e\u043a<\/td><\/tr>
\u0420\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0443\u0435\u043c\u043e\u0435 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435<\/strong><\/td>0.01 \u2013 1.0%<\/td><\/tr>
\u0420\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u043e\u0441\u0442\u044c<\/strong><\/td>Insoluble in water; soluble in ethanol and oils; soluble in propylene glycol with gentle heating<\/td><\/tr>
\u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u043f\u0440\u0435\u0438\u043c\u0443\u0449\u0435\u0441\u0442\u0432\u0430<\/strong><\/td>Anti-inflammatory, antibacterial, antioxidant, redness reduction, anti-glycation<\/td><\/tr>
\u041e\u0431\u0440\u0430\u0431\u043e\u0442\u043a\u0430<\/strong><\/td>Dissolve in propylene glycol with gentle heating and add to formulation. Avoid prolonged heating.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00ae PAE Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes. Paeonol is listed in China’s Inventory of Existing Cosmetic Ingredients (2021 Edition) and is considered safe under normal, reasonable, and foreseeable conditions of use<\/a><\/a>. The following maximum historical use concentrations are established based on marketed products<\/a><\/a>:<\/p>\n\n\n\n

 <\/strong> <\/strong> <\/strong>\u041e\u0431\u043b\u0430\u0441\u0442\u044c \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f<\/strong><\/strong><\/td>Usage Type<\/strong><\/strong><\/td>\u041c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u0430\u044f \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u0430\u044f \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f<\/strong><\/strong><\/td><\/tr>
Full body<\/strong><\/td>Leave-on<\/td>0.2%<\/td><\/tr>
Full body<\/strong><\/td>Rinse-off<\/td>0.3%<\/td><\/tr>
Face (incl. neck)<\/strong><\/td>Leave-on<\/td>0.3%<\/td><\/tr>
Eye area<\/strong><\/td>Leave-on<\/td>0.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u041f\u0440\u0438\u043c\u0435\u0447\u0430\u043d\u0438\u0435:<\/strong> For rinse-off products, the same concentrations as leave-on apply for each corresponding area. For eye area products, additional eye irritation assessment is required<\/a>.<\/p>\n\n\n\n

\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u044b \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f<\/strong><\/strong><\/h3>\n\n\n\n
\u0412\u044b\u0433\u043e\u0434\u0430<\/strong><\/strong><\/td>\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c<\/strong><\/strong><\/td><\/tr>
Antibacterial<\/strong><\/td>Exhibits potent antibacterial activity against E. coli, S. aureus, and S. epidermidis with a MIC of 62.5 mg\/mL<\/a><\/a>. Recent research confirms efficacy against acne-associated bacteria including Cutibacterium acnes and S. aureus<\/a>.<\/td><\/tr>
\u041f\u0440\u043e\u0442\u0438\u0432\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0435 \u0441\u0440\u0435\u0434\u0441\u0442\u0432\u043e<\/strong><\/td>Suppresses key inflammatory mediators, reducing erythema and swelling<\/a>. Has demonstrated therapeutic effects on acute skin eczema and pruritus<\/a><\/a>.<\/td><\/tr>
\u0410\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442<\/strong><\/td>Scavenges oxygen free radicals, mitigates oxidative stress<\/a><\/a>.<\/td><\/tr>
Redness Reduction<\/strong><\/td>Calms irritated skin, reduces visible redness<\/a>.<\/td><\/tr>
Skin Brightening<\/strong><\/td>Inhibits tyrosinase activity to help even skin tone<\/a><\/a>.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u041f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u043e\u0432<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE is a versatile skin conditioning agent suitable for a wide range of product categories:<\/p>\n\n\n\n

\u041a\u0430\u0442\u0435\u0433\u043e\u0440\u0438\u044f \u0442\u043e\u0432\u0430\u0440\u0430<\/strong><\/strong><\/td>\u041f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u044f<\/strong><\/strong><\/td><\/tr>
\u0423\u0445\u043e\u0434 \u0437\u0430 \u043a\u043e\u0436\u0435\u0439<\/strong><\/td>Masks, creams, serums for soothing, anti-itch, and redness-reducing effects<\/td><\/tr>
Hair & Body Care<\/strong><\/td>Shampoos, body washes, conditioners<\/td><\/tr>
Oral Care<\/strong><\/td>Toothpaste, mouthwash (unique natural cooling fragrance helps eliminate oral odor)<\/a><\/a><\/td><\/tr>
\u0421\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435<\/strong><\/td>Plant-based antimicrobial agent and preservative booster<\/td><\/tr>
Acne Management<\/strong><\/td>Adjunctive skincare for anti-inflammatory and antibacterial support<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00ae PAE from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

\u0411\u043b\u0430\u0433\u043e\u0434\u0430\u0440\u044f \u0431\u043e\u043b\u0435\u0435 \u0447\u0435\u043c 20-\u043b\u0435\u0442\u043d\u0435\u043c\u0443 \u043e\u043f\u044b\u0442\u0443 \u0440\u0430\u0431\u043e\u0442\u044b \u043a\u043e\u043c\u043f\u0430\u043d\u0438\u044f ZLEY\u00ae \u043f\u0440\u0435\u0432\u0440\u0430\u0442\u0438\u043b\u0430\u0441\u044c \u0432 \u0441\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0435 \u043f\u0440\u0435\u0434\u043f\u0440\u0438\u044f\u0442\u0438\u0435, \u043e\u0431\u044a\u0435\u0434\u0438\u043d\u044f\u044e\u0449\u0435\u0435 \u043d\u0430\u0443\u0447\u043d\u044b\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f, \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0441\u0442\u0432\u043e, \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u044c \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0430 \u0438 \u0441\u0431\u044b\u0442. \u041c\u044b \u0441\u0442\u0440\u0435\u043c\u0438\u043c\u0441\u044f \u043f\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u0442\u044c \u0441\u044b\u0440\u044c\u0435 \u0438 \u043f\u043e\u043b\u0443\u0444\u0430\u0431\u0440\u0438\u043a\u0430\u0442\u044b \u0434\u043b\u044f \u0441\u0440\u0435\u0434\u0441\u0442\u0432 \u043b\u0438\u0447\u043d\u043e\u0439 \u0433\u0438\u0433\u0438\u0435\u043d\u044b \u0432\u044b\u0441\u043e\u0447\u0430\u0439\u0448\u0435\u0433\u043e \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0430, \u0430 \u0442\u0430\u043a\u0436\u0435 \u043f\u0440\u0435\u0434\u043b\u0430\u0433\u0430\u0442\u044c \u0438\u043d\u0434\u0438\u0432\u0438\u0434\u0443\u0430\u043b\u044c\u043d\u044b\u0435 \u0440\u0435\u0446\u0435\u043f\u0442\u0443\u0440\u043d\u044b\u0435 \u0440\u0435\u0448\u0435\u043d\u0438\u044f, \u043e\u0442\u0432\u0435\u0447\u0430\u044e\u0449\u0438\u0435 \u0440\u0430\u0437\u043d\u043e\u043e\u0431\u0440\u0430\u0437\u043d\u044b\u043c \u043f\u043e\u0442\u0440\u0435\u0431\u043d\u043e\u0441\u0442\u044f\u043c \u043a\u043b\u0438\u0435\u043d\u0442\u043e\u0432. \u041d\u0430\u0448\u0430 \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u0430\u044f \u0441\u0435\u0442\u044c \u043f\u043e\u0441\u0442\u0430\u0432\u043e\u043a \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0438\u0432\u0430\u0435\u0442 \u043d\u0430\u0434\u0435\u0436\u043d\u043e\u0435 \u043e\u0431\u0441\u043b\u0443\u0436\u0438\u0432\u0430\u043d\u0438\u0435 \u043a\u043b\u0438\u0435\u043d\u0442\u043e\u0432 \u0432 \u0431\u043e\u043b\u0435\u0435 \u0447\u0435\u043c 60 \u0441\u0442\u0440\u0430\u043d\u0430\u0445.<\/p>\n\n\n\n

\u042d\u043b\u0435\u043a\u0442\u0440\u043e\u043d\u043d\u0430\u044f \u043f\u043e\u0447\u0442\u0430:<\/strong> services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n

\u041a\u0430\u043a\u0443\u044e \u0442\u0435\u0445\u043d\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u043a\u0443 \u0432\u044b \u043c\u043e\u0436\u0435\u0442\u0435 \u043e\u0436\u0438\u0434\u0430\u0442\u044c?<\/strong><\/strong><\/h3>\n\n\n\n

\u041a\u0430\u043a \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u043f\u043e\u0441\u0442\u0430\u0432\u0449\u0438\u043a, ZLEY\u00ae \u043f\u0440\u0435\u0434\u043b\u0430\u0433\u0430\u0435\u0442 \u0446\u0435\u043d\u043d\u043e\u0441\u0442\u044c, \u0432\u044b\u0445\u043e\u0434\u044f\u0449\u0443\u044e \u0437\u0430 \u0440\u0430\u043c\u043a\u0438 \u0441\u0430\u043c\u043e\u0433\u043e \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0430:<\/p>\n\n\n\n