ZLEY®HPA-Hydroxyphenyl Propamidobenzoic Acid is derived from oats. Oats (Avena sativa) are a globally cultivated crop and a heart-healthy food, primarily due to their richness in beta-glucans. For centuries, oats have been used not only as a food source but also for their skin-soothing properties. Clinical trials have demonstrated that oats are effective in relieving dry skin itching, reducing inflammation, and alleviating skin redness. Recent research has revealed that the anti-inflammatory and anti-itch bioactive components are oat alkaloids. In the field of skin anti-allergy applications, oat alkaloids are increasingly widely used. For the first time, researchers have confirmed that the traditional use of colloidal oats for skin soothing is actually attributable to the bioactivity of oat alkaloids in calming the skin and providing anti-allergic effects.