ZLEY®577PRO – 4-Butylresorcinol Liposome-135:
Liposome Targeted Delivery; Targets Melanocyte Stem Cells, Long-Term Sustained Release, Gentle Brightening & Spot Correction
Product Overview
ZLEY®577PRO (4-Butylresorcinol Liposome-135) features liposome–targeted delivery technology that protects the brightening active “577” (4-Butylresorcinol) and delivers it directly to the basal layer of the skin. The system provides sustained release of 577, targeting melanocyte stem cells and acting at both melanin synthesis and post‑synthesis stages to synergistically inhibit melanin production, fade surface pigmentation, and deliver gentle brightening and spot‑correcting effects.
ZLEY® is a professional supplier of 4-Butylresorcinol Liposome-135 (CAS: 7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7), providing stable quality, technical support, and global delivery covering over 60 countries.
ZLEY®577PRO Product Information
| Parameter | Specification |
| INCI Name | Water, PEG-40 Hydrogenated Castor Oil, Butylene Glycol, 4-Butylresorcinol, Lecithin, 1,2-Hexanediol, Tocopheryl Acetate |
| CAS Numbers | 7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7 |
| Appearance | Yellow to dark yellow liquid, characteristic odor |
| Active Content (4-Butylresorcinol) | 12 – 15% |
| Recommended Usage | 1 – 10% |
| Solubility | Alcohol-soluble, water-dispersible |
| Recommended Formulation pH | 4.5 – 6.0 |
| Key Benefits | Brightening & spot correction, antioxidant & radiance enhancement |
| Storage Note | Protect from high temperatures and light |
Is ZLEY®577PRO Safe?
Yes. ZLEY®577PRO is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following maximum concentrations:
| Product Type | Maximum Safe Concentration |
| Facial toners | ≤ 4.3% |
| Emulsions / Lotions | ≤ 9.0% |
| Face creams | ≤ 15.6% |
| Serums / Essences | ≤ 18.3% |
| Body creams / lotions | ≤ 1.6% |
At these concentrations, it does not pose a risk to human health.
Product Applications
In cosmetics and skincare, ZLEY®577PRO functions primarily as a skin conditioning agent. It is suitable for emulsions, creams, gels, and water-based formulations, making it ideal for brightening and spot-correcting products.
Product Development Philosophy
To address the three major challenges of 4-Butylresorcinol (“577”) – strong irritation, low stability, and poor water solubility – ZLEY®’s R&D team developed ZLEY®577PRO. Using liposome-targeted delivery technology, it protects the active ingredient “577” during delivery to the basal layer, provides long-term sustained release, targets melanocyte stem cells, inhibits melanin production, fades surface pigmentation, and delivers gentle brightening and spot-correcting efficacy.
Why Source ZLEY®577PRO from ZLEY®?
With over 20 years of dedicated experience, ZLEY® has evolved into a modern enterprise integrating R&D, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.
Email: [email protected]
What Technical Support Can You Expect?
As a specialized supplier, ZLEY® offers value beyond the product itself:
- Formulation Support: Basic formulation recommendations, combination suggestions, and processing guidance
- Regulatory Consulting: Assistance with interpreting compliance requirements for target markets
- Quality Assurance: Consistent product quality, competitive pricing, and reliable global logistics
- Market Intelligence: Latest market trends and ingredient application insights
Frequently Asked Questions (FAQ)
Q1: How does the liposome delivery system work?
A: The liposome system encapsulates 4-Butylresorcinol within lipid bilayers, protecting it from degradation and enabling efficient transport across the stratum corneum. It delivers the active directly to the basal layer where melanocyte stem cells reside, and releases it gradually over time for sustained brightening efficacy.
Q2: What is the recommended usage level for ZLEY®577PRO?
A: The recommended usage range is 1–10% depending on product type and desired efficacy. Specific safe maximums by product category apply (see Safety section above).
Q3: Is ZLEY®577PRO suitable for sensitive skin?
A: Yes. The liposome encapsulation provides controlled, sustained release of the active ingredient, significantly reducing the irritation potential compared to unencapsulated 4-Butylresorcinol. This makes it suitable for sensitive skin formulations.
Q4: What skin concerns does ZLEY®577PRO address?
A: It addresses hyperpigmentation concerns including melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), and uneven skin tone, while also providing antioxidant and radiance-enhancing benefits.