{"id":9730,"date":"2026-08-19T15:51:45","date_gmt":"2026-08-19T07:51:45","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9730"},"modified":"2026-08-19T15:51:45","modified_gmt":"2026-08-19T07:51:45","slug":"non-preservative-antimicrobial-synergist-for-mild-safe-formulations","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/ja\/non-preservative-antimicrobial-synergist-for-mild-safe-formulations\/","title":{"rendered":"\u30de\u30a4\u30eb\u30c9\u3067\u5b89\u5168\u306a\u88fd\u5264\u5411\u3051\u306e\u3001\u9632\u8150\u5264\u3092\u542b\u307e\u306a\u3044\u6297\u83cc\u76f8\u4e57\u5264"},"content":{"rendered":"

ZLEY\u00aeBIOCARE-PPD \u2013 Phenoxypropanediol (CAS 538-43-2): <\/strong><\/strong><\/h2>\n\n\n\n

\u30de\u30a4\u30eb\u30c9\u3067\u5b89\u5168\u306a\u88fd\u5264\u5411\u3051\u306e\u3001\u9632\u8150\u5264\u3092\u542b\u307e\u306a\u3044\u6297\u83cc\u76f8\u4e57\u5264<\/strong><\/strong><\/h2>\n\n\n\n
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<\/figcaption><\/figure>\n\n\n\n

\u88fd\u54c1\u6982\u8981<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00aeBIOCARE-PPD (INCI: Phenoxypropanediol, chemical name: 3-Phenoxy-1,2-propanediol) is structurally similar to Chlorphenesin. However, it is not classified as a traditional preservative<\/strong> but rather as a synergistic antimicrobial booster<\/strong>.<\/p>\n\n\n\n

Phenoxypropanediol inhibits microbial growth by disrupting cell membranes, blocking the transport of cellular matrices in bacteria, and allowing the efflux of certain cellular components to impair normal bacterial metabolism.<\/p>\n\n\n\n

As a potent broad-spectrum antimicrobial agent, it is effective against Gram-positive bacteria, Gram-negative bacteria, molds, and yeasts. It helps reduce the amount of other preservatives needed in formulations, making it an ideal choice for preservative-free concepts<\/strong> \u305d\u3057\u3066 \u654f\u611f\u808c<\/strong> applications.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Phenoxypropanediol (CAS 538-43-2), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00aeBIOCARE-PPD Product Information<\/strong><\/strong><\/h3>\n\n\n\n
\u30d1\u30e9\u30e1\u30fc\u30bf<\/td>\u4ed5\u69d8<\/td><\/tr>
INCI\u540d<\/strong><\/td>\u30d5\u30a7\u30ce\u30ad\u30b7\u30d7\u30ed\u30d1\u30f3\u30b8\u30aa\u30fc\u30eb<\/td><\/tr>
CAS\u756a\u53f7<\/strong><\/td>538-43-2<\/td><\/tr>
\u5916\u89b3<\/strong><\/td>\u767d\u8272\u304b\u3089\u30aa\u30d5\u30db\u30ef\u30a4\u30c8\u8272\u306e\u7d50\u6676<\/td><\/tr>
Key Benefit<\/strong><\/td>Non-preservative antimicrobial synergist (reduces traditional preservative usage)<\/td><\/tr>
\u63a8\u5968\u4f7f\u7528\u6cd5<\/strong><\/td>Face (incl. neck) \/ Leave-on: \u2264 0.5%<\/td><\/tr>
\u6eb6\u89e3\u5ea6<\/strong><\/td>Soluble in water and polyols at room temperature (e.g., 1,2-Pentanediol, 1,2-Hexanediol, Butylene Glycol, 1,3-Propanediol, etc.)<\/td><\/tr>
\u52a0\u5de5<\/strong><\/td>Pre-dissolve in water or polyols, then add to the formulation and mix thoroughly<\/td><\/tr>
Suitable Applications<\/strong><\/td>Transparent water-based systems, emulsions, facial cleansers, shampoos, wet wipes \u2013 both leave-on and rinse-off products<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00aeBIOCARE-PPD Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes.<\/strong> It is permitted at \u22640.5%<\/strong> in leave-on facial (including neck) products. It is allowed in the EU, China, the USA, and other major markets. It is not listed as a preservative<\/strong> in regulatory positive lists, offering greater formulation flexibility.<\/p>\n\n\n\n

\u4e3b\u306a\u5229\u70b9<\/strong><\/strong><\/h3>\n\n\n\n
\u5229\u70b9<\/strong><\/strong><\/td>\u8aac\u660e<\/strong><\/strong><\/td><\/tr>
Safe & Mild<\/strong><\/td>Excellent for sensitive skin and “preservative-free” concepts<\/td><\/tr>
Broad-Spectrum Efficacy<\/strong><\/td>Effective against bacteria, molds, and yeasts<\/td><\/tr>
Synergistic Booster<\/strong><\/td>Reduces the required amount of traditional preservatives<\/td><\/tr>
Excellent Compatibility<\/strong><\/td>Works across multiple formulation types<\/td><\/tr>
Good Stability<\/strong><\/td>Reliable performance under normal manufacturing conditions<\/td><\/tr>
Cost-Effective<\/strong><\/td>Efficient at low usage levels<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00aeBIOCARE-PPD from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

With over 20 years of integrated R&D, production, quality control, and sales experience, ZLEY\u00ae is committed to providing premium personal care raw materials and customized solutions. Our global delivery network serves customers in over 60 countries.<\/p>\n\n\n\n

\u3069\u306e\u3088\u3046\u306a\u30c6\u30af\u30cb\u30ab\u30eb\u30b5\u30dd\u30fc\u30c8\u304c\u53d7\u3051\u3089\u308c\u307e\u3059\u304b\uff1f<\/strong><\/strong><\/h3>\n\n\n\n