{"id":9641,"date":"2026-07-22T15:26:36","date_gmt":"2026-07-22T07:26:36","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9641"},"modified":"2026-07-22T15:26:36","modified_gmt":"2026-07-22T07:26:36","slug":"pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/ja\/pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent\/","title":{"rendered":"\u00a0\u533b\u85ac\u54c1\u30b0\u30ec\u30fc\u30c9\u306e\u6709\u52b9\u6210\u5206 \u2013 \u93ae\u9759\u4f5c\u7528\u3001\u304b\u3086\u307f\u6b62\u3081\u3001\u6297\u83cc\u4f5c\u7528"},"content":{"rendered":"

ZLEY\u00ae PAE \u2013 Paeonol (CAS 552-41-0):<\/strong><\/strong><\/h2>\n\n\n\n

 \u533b\u85ac\u54c1\u30b0\u30ec\u30fc\u30c9\u306e\u6709\u52b9\u6210\u5206 \u2013 \u93ae\u9759\u4f5c\u7528\u3001\u304b\u3086\u307f\u6b62\u3081\u3001\u6297\u83cc\u4f5c\u7528<\/strong><\/strong><\/h2>\n\n\n\n
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<\/figcaption><\/figure>\n\n\n\n

\u88fd\u54c1\u6982\u8981<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE (Paeonol), also known as Peonol<\/strong> \u307e\u305f\u306f 2-hydroxy-4-methoxyacetophenone<\/strong>, is an active monomer compound extracted from the root bark of the peony plant (Paeonia suffruticosa) or the dried roots of Cynanchum paniculatum<\/a><\/a>. As a small-molecule phenolic compound, it offers a unique combination of antibacterial, anti-inflammatory, redness-reducing, and antioxidant benefits<\/a><\/a>.<\/p>\n\n\n\n

Paeonol has a long history of clinical use in China, with injectable formulations dating back to the 1970s. It is widely used in oral care, hair care, skincare, and cosmetic products<\/a><\/a>. Recent research has also highlighted its potential as an anti-acne adjuvant<\/strong>, with studies showing that it suppresses key inflammatory mediators, scavenges free radicals, and inhibits melanogenesis<\/a>.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Paeonol (CAS 552-41-0), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00ae PAE Product Information<\/strong><\/strong><\/h3>\n\n\n\n
\u30d1\u30e9\u30e1\u30fc\u30bf<\/td>\u4ed5\u69d8<\/td><\/tr>
INCI\u540d<\/strong><\/td>\u30d1\u30a8\u30aa\u30ce\u30eb<\/td><\/tr>
CAS\u756a\u53f7<\/strong><\/td>552-41-0<\/td><\/tr>
\u5916\u89b3<\/strong><\/td>\u767d\u8272\u307e\u305f\u306f\u30aa\u30d5\u30db\u30ef\u30a4\u30c8\u306e\u7d50\u6676\u6027\u7c89\u672b<\/td><\/tr>
\u63a8\u5968\u4f7f\u7528\u6cd5<\/strong><\/td>0.01 \u2013 1.0%<\/td><\/tr>
\u6eb6\u89e3\u5ea6<\/strong><\/td>Insoluble in water; soluble in ethanol and oils; soluble in propylene glycol with gentle heating<\/td><\/tr>
\u4e3b\u306a\u30e1\u30ea\u30c3\u30c8<\/strong><\/td>Anti-inflammatory, antibacterial, antioxidant, redness reduction, anti-glycation<\/td><\/tr>
\u52a0\u5de5<\/strong><\/td>Dissolve in propylene glycol with gentle heating and add to formulation. Avoid prolonged heating.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00ae PAE Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes. Paeonol is listed in China’s Inventory of Existing Cosmetic Ingredients (2021 Edition) and is considered safe under normal, reasonable, and foreseeable conditions of use<\/a><\/a>. The following maximum historical use concentrations are established based on marketed products<\/a><\/a>:<\/p>\n\n\n\n

 <\/strong> <\/strong> <\/strong>\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u30a8\u30ea\u30a2<\/strong><\/strong><\/td>Usage Type<\/strong><\/strong><\/td>\u6700\u5927\u5b89\u5168\u6fc3\u5ea6<\/strong><\/strong><\/td><\/tr>
Full body<\/strong><\/td>Leave-on<\/td>0.2%<\/td><\/tr>
Full body<\/strong><\/td>Rinse-off<\/td>0.3%<\/td><\/tr>
Face (incl. neck)<\/strong><\/td>Leave-on<\/td>0.3%<\/td><\/tr>
Eye area<\/strong><\/td>Leave-on<\/td>0.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Note:<\/strong> For rinse-off products, the same concentrations as leave-on apply for each corresponding area. For eye area products, additional eye irritation assessment is required<\/a>.<\/p>\n\n\n\n

\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/strong><\/h3>\n\n\n\n
\u5229\u70b9<\/strong><\/strong><\/td>\u30e1\u30ab\u30cb\u30ba\u30e0<\/strong><\/strong><\/td><\/tr>
Antibacterial<\/strong><\/td>Exhibits potent antibacterial activity against E. coli, S. aureus, and S. epidermidis with a MIC of 62.5 mg\/mL<\/a><\/a>. Recent research confirms efficacy against acne-associated bacteria including Cutibacterium acnes and S. aureus<\/a>.<\/td><\/tr>
\u6297\u708e\u75c7<\/strong><\/td>Suppresses key inflammatory mediators, reducing erythema and swelling<\/a>. Has demonstrated therapeutic effects on acute skin eczema and pruritus<\/a><\/a>.<\/td><\/tr>
\u6297\u9178\u5316\u7269\u8cea<\/strong><\/td>Scavenges oxygen free radicals, mitigates oxidative stress<\/a><\/a>.<\/td><\/tr>
Redness Reduction<\/strong><\/td>Calms irritated skin, reduces visible redness<\/a>.<\/td><\/tr>
Skin Brightening<\/strong><\/td>Inhibits tyrosinase activity to help even skin tone<\/a><\/a>.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u88fd\u54c1\u7528\u9014<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE is a versatile skin conditioning agent suitable for a wide range of product categories:<\/p>\n\n\n\n

\u5546\u54c1\u30ab\u30c6\u30b4\u30ea<\/strong><\/strong><\/td>\u30a2\u30d7\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3<\/strong><\/strong><\/td><\/tr>
\u30b9\u30ad\u30f3\u30b1\u30a2<\/strong><\/td>Masks, creams, serums for soothing, anti-itch, and redness-reducing effects<\/td><\/tr>
Hair & Body Care<\/strong><\/td>Shampoos, body washes, conditioners<\/td><\/tr>
Oral Care<\/strong><\/td>Toothpaste, mouthwash (unique natural cooling fragrance helps eliminate oral odor)<\/a><\/a><\/td><\/tr>
\u4fdd\u5b58<\/strong><\/td>Plant-based antimicrobial agent and preservative booster<\/td><\/tr>
Acne Management<\/strong><\/td>Adjunctive skincare for anti-inflammatory and antibacterial support<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00ae PAE from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

20\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u308b\u732e\u8eab\u7684\u306a\u5b9f\u7e3e\u3092\u7a4d\u307f\u91cd\u306d\u3066\u304d\u305fZLEY\u00ae\u306f\u3001\u7814\u7a76\u3001\u751f\u7523\u3001\u54c1\u8cea\u7ba1\u7406\u3001\u8ca9\u58f2\u3092\u4e00\u4f53\u5316\u3057\u305f\u73fe\u4ee3\u7684\u306a\u4f01\u696d\u3078\u3068\u767a\u5c55\u3092\u9042\u3052\u307e\u3057\u305f\u3002\u5f53\u793e\u306f\u3001\u304a\u5ba2\u69d8\u306e\u591a\u69d8\u306a\u30cb\u30fc\u30ba\u306b\u5fdc\u3048\u308b\u305f\u3081\u3001\u6700\u9ad8\u54c1\u8cea\u306e\u30d1\u30fc\u30bd\u30ca\u30eb\u30b1\u30a2\u7528\u539f\u6599\u3001\u534a\u88fd\u54c1\u3001\u304a\u3088\u3073\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3055\u308c\u305f\u51e6\u65b9\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u306e\u63d0\u4f9b\u306b\u5c3d\u529b\u3057\u3066\u3044\u307e\u3059\u3002\u5f53\u793e\u306e\u30b0\u30ed\u30fc\u30d0\u30eb\u306a\u914d\u9001\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u3088\u308a\u300160\u30ab\u56fd\u4ee5\u4e0a\u306e\u304a\u5ba2\u69d8\u306b\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u30b5\u30fc\u30d3\u30b9\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002.<\/p>\n\n\n\n

E\u30e1\u30fc\u30eb<\/strong> services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n

\u3069\u306e\u3088\u3046\u306a\u30c6\u30af\u30cb\u30ab\u30eb\u30b5\u30dd\u30fc\u30c8\u304c\u53d7\u3051\u3089\u308c\u307e\u3059\u304b\uff1f<\/strong><\/strong><\/h3>\n\n\n\n

\u5c02\u9580\u30b5\u30d7\u30e9\u30a4\u30e4\u30fc\u3068\u3057\u3066\u3001ZLEY\u00ae\u306f\u88fd\u54c1\u305d\u306e\u3082\u306e\u3092\u8d85\u3048\u305f\u4fa1\u5024\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\uff1a<\/p>\n\n\n\n