リポソームによる標的送達；メラノサイト幹細胞を標的とし、長期にわたる持続放出、肌に優しい美白効果とシミの改善

ZLEY®577PRO – 4-Butylresorcinol Liposome-135:

リポソームによる標的送達；メラノサイト幹細胞を標的とし、長期にわたる持続放出、肌に優しい美白効果とシミの改善

製品概要

ZLEY®577PRO (4-Butylresorcinol Liposome-135) features liposome–targeted delivery technology that protects the brightening active “577” (4-Butylresorcinol) and delivers it directly to the basal layer of the skin. The system provides sustained release of 577, targeting melanocyte stem cells and acting at both melanin synthesis and post‑synthesis stages to synergistically inhibit melanin production, fade surface pigmentation, and deliver gentle brightening and spot‑correcting effects.

ZLEY® is a professional supplier of 4-Butylresorcinol Liposome-135 (CAS: 7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7), providing stable quality, technical support, and global delivery covering over 60 countries.

ZLEY®577PRO Product Information

Is ZLEY®577PRO Safe?

Yes. ZLEY®577PRO is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following maximum concentrations:

At these concentrations, it does not pose a risk to human health.

製品用途

In cosmetics and skincare, ZLEY®577PRO functions primarily as a 皮膚コンディショニング剤. It is suitable for emulsions, creams, gels, and water-based formulations, making it ideal for brightening and spot-correcting products.

製品開発の理念

To address the three major challenges of 4-Butylresorcinol (“577”) – strong irritation, low stability, and poor water solubility – ZLEY®’s R&D team developed ZLEY®577PRO. Using liposome-targeted delivery technology, it protects the active ingredient “577” during delivery to the basal layer, provides long-term sustained release, targets melanocyte stem cells, inhibits melanin production, fades surface pigmentation, and delivers gentle brightening and spot-correcting efficacy.

Why Source ZLEY®577PRO from ZLEY®?

With over 20 years of dedicated experience, ZLEY® has evolved into a modern enterprise integrating R&D, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.

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どのようなテクニカルサポートが受けられますか？

専門サプライヤーとして、ZLEY®は製品そのものを超えた価値を提供しています：

• 処方サポート: 基本的な配合の推奨事項、配合の提案、および加工に関する指針
• 規制コンサルティング: 対象市場におけるコンプライアンス要件の解釈に関する支援
• 品質保証： Consistent product quality, competitive pricing, and reliable global logistics
• 市場情報： 最新の市場動向と原料の活用に関する知見

よくある質問（FAQ）

Q1: How does the liposome delivery system work?

A: The liposome system encapsulates 4-Butylresorcinol within lipid bilayers, protecting it from degradation and enabling efficient transport across the stratum corneum. It delivers the active directly to the basal layer where melanocyte stem cells reside, and releases it gradually over time for sustained brightening efficacy.

Q2: What is the recommended usage level for ZLEY®577PRO?

A: 推奨使用範囲は 1–10% depending on product type and desired efficacy. Specific safe maximums by product category apply (see Safety section above).

Q3: Is ZLEY®577PRO suitable for sensitive skin?

A: Yes. The liposome encapsulation provides controlled, sustained release of the active ingredient, significantly reducing the irritation potential compared to unencapsulated 4-Butylresorcinol. This makes it suitable for sensitive skin formulations.

Q4: What skin concerns does ZLEY®577PRO address?

A: It addresses hyperpigmentation concerns including melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), and uneven skin tone, while also providing antioxidant and radiance-enhancing benefits.