{"id":9641,"date":"2026-07-22T15:26:36","date_gmt":"2026-07-22T07:26:36","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9641"},"modified":"2026-07-22T15:26:36","modified_gmt":"2026-07-22T07:26:36","slug":"pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/it\/pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent\/","title":{"rendered":"\u00a0Principio attivo di grado farmaceutico \u2013 Agente lenitivo, antipruriginoso e antimicrobico"},"content":{"rendered":"

ZLEY\u00ae PAE \u2013 Paeonol (CAS 552-41-0):<\/strong><\/strong><\/h2>\n\n\n\n

 Principio attivo di grado farmaceutico \u2013 Agente lenitivo, antipruriginoso e antimicrobico<\/strong><\/strong><\/h2>\n\n\n\n
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Panoramica del prodotto<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE (Paeonol), also known as Peonol<\/strong> oppure 2-hydroxy-4-methoxyacetophenone<\/strong>, is an active monomer compound extracted from the root bark of the peony plant (Paeonia suffruticosa) or the dried roots of Cynanchum paniculatum<\/a><\/a>. As a small-molecule phenolic compound, it offers a unique combination of antibacterial, anti-inflammatory, redness-reducing, and antioxidant benefits<\/a><\/a>.<\/p>\n\n\n\n

Paeonol has a long history of clinical use in China, with injectable formulations dating back to the 1970s. It is widely used in oral care, hair care, skincare, and cosmetic products<\/a><\/a>. Recent research has also highlighted its potential as an anti-acne adjuvant<\/strong>, with studies showing that it suppresses key inflammatory mediators, scavenges free radicals, and inhibits melanogenesis<\/a>.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Paeonol (CAS 552-41-0), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00ae PAE Product Information<\/strong><\/strong><\/h3>\n\n\n\n
Parametro<\/td>Specifiche<\/td><\/tr>
Nome INCI<\/strong><\/td>Paeonol<\/td><\/tr>
Numero CAS<\/strong><\/td>552-41-0<\/td><\/tr>
Aspetto<\/strong><\/td>Polvere cristallina bianca o biancastra<\/td><\/tr>
Uso consigliato<\/strong><\/td>0.01 \u2013 1.0%<\/td><\/tr>
Solubilit\u00e0<\/strong><\/td>Insoluble in water; soluble in ethanol and oils; soluble in propylene glycol with gentle heating<\/td><\/tr>
Vantaggi principali<\/strong><\/td>Anti-inflammatory, antibacterial, antioxidant, redness reduction, anti-glycation<\/td><\/tr>
Elaborazione<\/strong><\/td>Dissolve in propylene glycol with gentle heating and add to formulation. Avoid prolonged heating.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00ae PAE Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes. Paeonol is listed in China’s Inventory of Existing Cosmetic Ingredients (2021 Edition) and is considered safe under normal, reasonable, and foreseeable conditions of use<\/a><\/a>. The following maximum historical use concentrations are established based on marketed products<\/a><\/a>:<\/p>\n\n\n\n

 <\/strong> <\/strong> <\/strong>Area di applicazione<\/strong><\/strong><\/td>Usage Type<\/strong><\/strong><\/td>Concentrazione massima di sicurezza<\/strong><\/strong><\/td><\/tr>
Full body<\/strong><\/td>Leave-on<\/td>0.2%<\/td><\/tr>
Full body<\/strong><\/td>Rinse-off<\/td>0.3%<\/td><\/tr>
Face (incl. neck)<\/strong><\/td>Leave-on<\/td>0.3%<\/td><\/tr>
Eye area<\/strong><\/td>Leave-on<\/td>0.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Nota:<\/strong> For rinse-off products, the same concentrations as leave-on apply for each corresponding area. For eye area products, additional eye irritation assessment is required<\/a>.<\/p>\n\n\n\n

Meccanismi d'azione<\/strong><\/strong><\/h3>\n\n\n\n
Vantaggio<\/strong><\/strong><\/td>Meccanismo<\/strong><\/strong><\/td><\/tr>
Antibacterial<\/strong><\/td>Exhibits potent antibacterial activity against E. coli, S. aureus, and S. epidermidis with a MIC of 62.5 mg\/mL<\/a><\/a>. Recent research confirms efficacy against acne-associated bacteria including Cutibacterium acnes and S. aureus<\/a>.<\/td><\/tr>
Antinfiammatorio<\/strong><\/td>Suppresses key inflammatory mediators, reducing erythema and swelling<\/a>. Has demonstrated therapeutic effects on acute skin eczema and pruritus<\/a><\/a>.<\/td><\/tr>
Antiossidante<\/strong><\/td>Scavenges oxygen free radicals, mitigates oxidative stress<\/a><\/a>.<\/td><\/tr>
Redness Reduction<\/strong><\/td>Calms irritated skin, reduces visible redness<\/a>.<\/td><\/tr>
Skin Brightening<\/strong><\/td>Inhibits tyrosinase activity to help even skin tone<\/a><\/a>.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Applicazioni del prodotto<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE is a versatile skin conditioning agent suitable for a wide range of product categories:<\/p>\n\n\n\n

Product Category<\/strong><\/strong><\/td>Applicazioni<\/strong><\/strong><\/td><\/tr>
Cura della pelle<\/strong><\/td>Masks, creams, serums for soothing, anti-itch, and redness-reducing effects<\/td><\/tr>
Hair & Body Care<\/strong><\/td>Shampoos, body washes, conditioners<\/td><\/tr>
Igiene orale<\/strong><\/td>Toothpaste, mouthwash (unique natural cooling fragrance helps eliminate oral odor)<\/a><\/a><\/td><\/tr>
Conservazione<\/strong><\/td>Plant-based antimicrobial agent and preservative booster<\/td><\/tr>
Acne Management<\/strong><\/td>Adjunctive skincare for anti-inflammatory and antibacterial support<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00ae PAE from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

Con oltre 20 anni di esperienza nel settore, ZLEY\u00ae si \u00e8 trasformata in un'azienda moderna che integra ricerca, produzione, controllo qualit\u00e0 e vendite. Ci impegniamo a fornire materie prime per la cura della persona, semilavorati e soluzioni di formulazione personalizzate della massima qualit\u00e0, per soddisfare le diverse esigenze dei clienti. La nostra rete di distribuzione globale garantisce un servizio affidabile ai clienti in oltre 60 paesi.<\/p>\n\n\n\n

E-mail:<\/strong> services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n

Che tipo di assistenza tecnica puoi aspettarti?<\/strong><\/strong><\/h3>\n\n\n\n

In qualit\u00e0 di fornitore specializzato, ZLEY\u00ae offre un valore che va oltre il prodotto stesso:<\/p>\n\n\n\n