{"id":9730,"date":"2026-08-19T15:51:45","date_gmt":"2026-08-19T07:51:45","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9730"},"modified":"2026-08-19T15:51:45","modified_gmt":"2026-08-19T07:51:45","slug":"non-preservative-antimicrobial-synergist-for-mild-safe-formulations","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/fr\/non-preservative-antimicrobial-synergist-for-mild-safe-formulations\/","title":{"rendered":"Synergiste antimicrobien sans conservateur pour des formulations douces et s\u00fbres"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>ZLEY\u00aeBIOCARE-PPD \u2013 Phenoxypropanediol (CAS 538-43-2): <\/strong><strong><\/strong><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Synergiste antimicrobien sans conservateur pour des formulations douces et s\u00fbres<\/strong><strong><\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"285\" src=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2.png\" alt=\"\" class=\"wp-image-9731\" title=\"\" srcset=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2.png 600w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-300x143.png 300w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-18x9.png 18w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-64x30.png 64w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption><\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Aper\u00e7u du produit<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00aeBIOCARE-PPD (INCI: Phenoxypropanediol, chemical name: 3-Phenoxy-1,2-propanediol) is structurally similar to Chlorphenesin. However, it is&nbsp;<strong>not classified as a traditional preservative<\/strong>&nbsp;but rather as a&nbsp;<strong>synergistic antimicrobial booster<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phenoxypropanediol inhibits microbial growth by disrupting cell membranes, blocking the transport of cellular matrices in bacteria, and allowing the efflux of certain cellular components to impair normal bacterial metabolism.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a potent broad-spectrum antimicrobial agent, it is effective against Gram-positive bacteria, Gram-negative bacteria, molds, and yeasts. It helps reduce the amount of other preservatives needed in formulations, making it an ideal choice for&nbsp;<strong>preservative-free concepts<\/strong>&nbsp;et&nbsp;<strong>peau sensible<\/strong>&nbsp;applications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae is a professional supplier of Phenoxypropanediol (CAS 538-43-2), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ZLEY\u00aeBIOCARE-PPD Product Information<\/strong><strong><\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>Param\u00e8tre<\/td><td>Sp\u00e9cifications<\/td><\/tr><tr><td><strong>Nom INCI<\/strong><\/td><td>Ph\u00e9noxypropanediol<\/td><\/tr><tr><td><strong>Num\u00e9ro CAS<\/strong><\/td><td>538-43-2<\/td><\/tr><tr><td><strong>Apparence<\/strong><\/td><td>Cristaux blancs \u00e0 blanc cass\u00e9<\/td><\/tr><tr><td><strong>Avantage principal<\/strong><\/td><td>Non-preservative antimicrobial synergist (reduces traditional preservative usage)<\/td><\/tr><tr><td><strong>Utilisation recommand\u00e9e<\/strong><\/td><td>Face (incl. neck) \/ Leave-on: \u2264 0.5%<\/td><\/tr><tr><td><strong>Solubilit\u00e9<\/strong><\/td><td>Soluble in water and polyols at room temperature (e.g., 1,2-Pentanediol, 1,2-Hexanediol, Butylene Glycol, 1,3-Propanediol, etc.)<\/td><\/tr><tr><td><strong>Traitement<\/strong><\/td><td>Pre-dissolve in water or polyols, then add to the formulation and mix thoroughly<\/td><\/tr><tr><td><strong>Suitable Applications<\/strong><\/td><td>Transparent water-based systems, emulsions, facial cleansers, shampoos, wet wipes \u2013 both leave-on and rinse-off products<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Is ZLEY\u00aeBIOCARE-PPD Safe?<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Oui.<\/strong>&nbsp;It is permitted at&nbsp;<strong>\u22640.5%<\/strong>&nbsp;in leave-on facial (including neck) products. It is allowed in the EU, China, the USA, and other major markets.&nbsp;<strong>It is not listed as a preservative<\/strong>&nbsp;in regulatory positive lists, offering greater formulation flexibility.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Principaux avantages<\/strong><strong><\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Avantage<\/strong><strong><\/strong><\/td><td><strong>Description<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Safe &amp; Mild<\/strong><\/td><td>Excellent for sensitive skin and &#8220;preservative-free&#8221; concepts<\/td><\/tr><tr><td><strong>Broad-Spectrum Efficacy<\/strong><\/td><td>Effective against bacteria, molds, and yeasts<\/td><\/tr><tr><td><strong>Synergistic Booster<\/strong><\/td><td>Reduces the required amount of traditional preservatives<\/td><\/tr><tr><td><strong>Excellent Compatibility<\/strong><\/td><td>Works across multiple formulation types<\/td><\/tr><tr><td><strong>Good Stability<\/strong><\/td><td>Reliable performance under normal manufacturing conditions<\/td><\/tr><tr><td><strong>Cost-Effective<\/strong><\/td><td>Efficient at low usage levels<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Why Source ZLEY\u00aeBIOCARE-PPD from ZLEY\u00ae?<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">With over 20 years of integrated R&amp;D, production, quality control, and sales experience, ZLEY\u00ae is committed to providing premium personal care raw materials and customized solutions. Our global delivery network serves customers in over 60 countries.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u00c0 quel type d'assistance technique pouvez-vous vous attendre ?<\/strong><strong><\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Soutien \u00e0 la formulation\u00a0:<\/strong>\u00a0Recommandations de base en mati\u00e8re de formulation, suggestions d'associations et conseils de mise en \u0153uvre<\/li>\n\n\n\n<li><strong>Conseil en mati\u00e8re de r\u00e9glementation\u00a0:<\/strong>\u00a0Target market compliance assistance<\/li>\n\n\n\n<li><strong>Assurance qualit\u00e9:<\/strong>\u00a0Une qualit\u00e9 constante, des prix comp\u00e9titifs et une logistique internationale fiable<\/li>\n\n\n\n<li><strong>Informations sur le march\u00e9 :<\/strong>\u00a0Latest trends and ingredient application insights<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Foire aux questions (FAQ)<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q1: Is Phenoxypropanediol a preservative?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: No. It is not listed as a preservative in regulatory positive lists (such as EU Annex V). It functions as a&nbsp;<strong>synergistic antimicrobial booster<\/strong>&nbsp;that enhances preservation systems while reducing the need for traditional preservatives.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q2 : Quelle est la dose d'utilisation recommand\u00e9e ?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">R : La dose d'utilisation recommand\u00e9e est de&nbsp;<strong>\u2264<\/strong><strong>&nbsp;<\/strong><strong>0.5%<\/strong>&nbsp;in leave-on facial (including neck) products. This concentration is compliant with EU, US, and Chinese regulations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q3: How does Phenoxypropanediol work?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It disrupts microbial cell membranes, blocks cellular matrix transport, and impairs normal bacterial metabolism, effectively inhibiting bacterial, mold, and yeast growth.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q4: What types of products is it suitable for?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It is suitable for transparent water-based systems, emulsions, facial cleansers, shampoos, and wet wipes, for both leave-on and rinse-off applications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q5: How can I request samples and technical documentation?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Please contact our export team:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Courriel :<\/strong>&nbsp;<a href=\"mailto:services@zleygroup.com\"><u>services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Include your company details, target product type, and target market for the most relevant information.<\/p>","protected":false},"excerpt":{"rendered":"<p>ZLEY\u00aeBIOCARE-PPD \u2013 Phenoxypropanediol (CAS 538-43-2): Non-Preservative Antimicrobial Synergist for Mild, Safe Formulations Product Overview ZLEY\u00aeBIOCARE-PPD (INCI: Phenoxypropanediol, chemical name: 3-Phenoxy-1,2-propanediol) [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9731,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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