{"id":9675,"date":"2026-08-05T16:22:18","date_gmt":"2026-08-05T08:22:18","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9675"},"modified":"2026-08-05T16:22:18","modified_gmt":"2026-08-05T08:22:18","slug":"liposome-targeted-delivery-targets-melanocyte-stem-cells-long-term-sustained-release-gentle-brightening-spot-correction","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/fr\/liposome-targeted-delivery-targets-melanocyte-stem-cells-long-term-sustained-release-gentle-brightening-spot-correction\/","title":{"rendered":"Administ\u00e9ration cibl\u00e9e par liposomes ; cible les cellules souches m\u00e9lanocytaires, lib\u00e9ration prolong\u00e9e, \u00e9claircissement en douceur et correction des taches"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>ZLEY\u00ae577PRO \u2013 4-Butylresorcinol Liposome-135: <\/strong><strong><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Administ\u00e9ration cibl\u00e9e par liposomes ; cible les cellules souches m\u00e9lanocytaires, lib\u00e9ration prolong\u00e9e, \u00e9claircissement en douceur et correction des taches<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"702\" height=\"575\" src=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472.png\" alt=\"\" class=\"wp-image-9676\" title=\"\" srcset=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472.png 702w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-300x246.png 300w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-15x12.png 15w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-600x491.png 600w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-64x52.png 64w\" sizes=\"(max-width: 702px) 100vw, 702px\" \/><figcaption><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Aper\u00e7u du produit<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae577PRO (4-Butylresorcinol Liposome-135) features&nbsp;<strong>liposome<\/strong><strong>\u2013<\/strong><strong>technologie de diffusion cibl\u00e9e<\/strong>&nbsp;that protects the brightening active &#8220;577&#8221; (4-Butylresorcinol) and delivers it directly to the basal layer of the skin. The system provides&nbsp;<strong>sustained release<\/strong>&nbsp;of 577, targeting melanocyte stem cells and acting at both melanin synthesis and post\u2011synthesis stages to synergistically inhibit melanin production, fade surface pigmentation, and deliver gentle brightening and spot\u2011correcting effects.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae is a professional supplier of 4-Butylresorcinol Liposome-135 (CAS: 7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>ZLEY\u00ae577PRO Product Information<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Param\u00e8tre<\/strong><strong><\/strong><\/td><td><strong>Sp\u00e9cifications<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Nom INCI<\/strong><\/td><td>Water, PEG-40 Hydrogenated Castor Oil, Butylene Glycol, 4-Butylresorcinol, Lecithin, 1,2-Hexanediol, Tocopheryl Acetate<\/td><\/tr><tr><td><strong>Num\u00e9ros CAS<\/strong><\/td><td>7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7<\/td><\/tr><tr><td><strong>Apparence<\/strong><\/td><td>Liquide de couleur jaune \u00e0 jaune fonc\u00e9, odeur caract\u00e9ristique<\/td><\/tr><tr><td><strong>Active Content (4-Butylresorcinol)<\/strong><\/td><td>12 \u2013 15%<\/td><\/tr><tr><td><strong>Utilisation recommand\u00e9e<\/strong><\/td><td>1 \u2013 10%<\/td><\/tr><tr><td><strong>Solubilit\u00e9<\/strong><\/td><td>Soluble dans l'alcool, dispersible dans l'eau<\/td><\/tr><tr><td><strong>pH recommand\u00e9 pour la formulation<\/strong><\/td><td>4.5 \u2013 6.0<\/td><\/tr><tr><td><strong>Principaux avantages<\/strong><\/td><td>Brightening &amp; spot correction, antioxidant &amp; radiance enhancement<\/td><\/tr><tr><td><strong>Storage Note<\/strong><\/td><td>Protect from high temperatures and light<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Is ZLEY\u00ae577PRO Safe?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Yes. ZLEY\u00ae577PRO is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following maximum concentrations:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Type de produit<\/strong><strong><\/strong><\/td><td><strong>Concentration maximale sans danger<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Facial toners<\/strong><\/td><td>\u2264 4.3%<\/td><\/tr><tr><td><strong>Emulsions \/ Lotions<\/strong><\/td><td>\u2264 9.0%<\/td><\/tr><tr><td><strong>Face creams<\/strong><\/td><td>\u2264 15.6%<\/td><\/tr><tr><td><strong>Serums \/ Essences<\/strong><\/td><td>\u2264 18.3%<\/td><\/tr><tr><td><strong>Body creams \/ lotions<\/strong><\/td><td>\u2264 1.6%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">At these concentrations, it does not pose a risk to human health.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Applications des produits<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In cosmetics and skincare, ZLEY\u00ae577PRO functions primarily as a&nbsp;<strong>agent de soin de la peau<\/strong>. Il convient aux \u00e9mulsions, cr\u00e8mes, gels et formulations \u00e0 base d'eau, ce qui en fait un ingr\u00e9dient id\u00e9al pour les produits \u00e9claircissants et anti-imperfections.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Philosophie de d\u00e9veloppement des produits<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To address the three major challenges of 4-Butylresorcinol (&#8220;577&#8221;) \u2013&nbsp;<strong>strong irritation, low stability, and poor water solubility<\/strong>&nbsp;\u2013 ZLEY\u00ae&#8217;s R&amp;D team developed ZLEY\u00ae577PRO. Using liposome-targeted delivery technology, it protects the active ingredient &#8220;577&#8221; during delivery to the basal layer, provides long-term sustained release, targets melanocyte stem cells, inhibits melanin production, fades surface pigmentation, and delivers gentle brightening and spot-correcting efficacy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why Source ZLEY\u00ae577PRO from ZLEY\u00ae?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Forte de plus de 20 ans d\u2019exp\u00e9rience dans ce domaine, ZLEY\u00ae s\u2019est d\u00e9velopp\u00e9e pour devenir une entreprise moderne int\u00e9grant la R&amp;D, la production, le contr\u00f4le qualit\u00e9 et la commercialisation. Nous nous engageons \u00e0 fournir des mati\u00e8res premi\u00e8res, des produits semi-finis et des solutions de formulation sur mesure de la plus haute qualit\u00e9 pour les soins personnels, afin de r\u00e9pondre aux besoins vari\u00e9s de nos clients. Notre r\u00e9seau de livraison mondial garantit un service fiable \u00e0 nos clients dans plus de 60 pays.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Courriel :<\/strong>&nbsp;<a href=\"mailto:services@zleygroup.com\"><u>services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u00c0 quel type d'assistance technique pouvez-vous vous attendre ?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">En tant que fournisseur sp\u00e9cialis\u00e9, ZLEY\u00ae offre une valeur ajout\u00e9e qui va au-del\u00e0 du produit lui-m\u00eame :<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Soutien \u00e0 la formulation\u00a0:<\/strong>\u00a0Recommandations de base en mati\u00e8re de formulation, suggestions d'associations et conseils de mise en \u0153uvre<\/li>\n\n\n\n<li><strong>Conseil en mati\u00e8re de r\u00e9glementation\u00a0:<\/strong>\u00a0Aide \u00e0 l'interpr\u00e9tation des exigences de conformit\u00e9 pour les march\u00e9s cibles<\/li>\n\n\n\n<li><strong>Assurance qualit\u00e9:<\/strong>\u00a0Une qualit\u00e9 constante des produits, des prix comp\u00e9titifs et une logistique internationale fiable<\/li>\n\n\n\n<li><strong>Informations sur le march\u00e9 :<\/strong>\u00a0Derni\u00e8res tendances du march\u00e9 et analyses sur l'utilisation des ingr\u00e9dients<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Foire aux questions (FAQ)<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>1<\/strong><strong>: How does the liposome delivery system work?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: The liposome system encapsulates 4-Butylresorcinol within lipid bilayers, protecting it from degradation and enabling efficient transport across the stratum corneum. It delivers the active directly to the basal layer where melanocyte stem cells reside, and releases it gradually over time for sustained brightening efficacy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>2<\/strong><strong>: What is the recommended usage level for ZLEY\u00ae577PRO?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">R : La plage d'utilisation recommand\u00e9e est de&nbsp;<strong>1\u201310%<\/strong>&nbsp;depending on product type and desired efficacy. Specific safe maximums by product category apply (see Safety section above).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>3<\/strong><strong>: Is ZLEY\u00ae577PRO suitable for sensitive skin?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: Yes. The liposome encapsulation provides controlled, sustained release of the active ingredient, significantly reducing the irritation potential compared to unencapsulated 4-Butylresorcinol. This makes it suitable for sensitive skin formulations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>4<\/strong><strong>: What skin concerns does ZLEY\u00ae577PRO address?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It addresses hyperpigmentation concerns including melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), and&nbsp;uneven skin tone, while also providing antioxidant and radiance-enhancing benefits.<\/p>","protected":false},"excerpt":{"rendered":"<p>ZLEY\u00ae577PRO \u2013 4-Butylresorcinol Liposome-135: Liposome Targeted Delivery; Targets Melanocyte Stem Cells, Long-Term Sustained Release, Gentle Brightening &amp; Spot Correction Product [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9676,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[69],"tags":[],"class_list":["post-9675","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-active-ingredients"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/posts\/9675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/comments?post=9675"}],"version-history":[{"count":0,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/posts\/9675\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/media\/9676"}],"wp:attachment":[{"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/media?parent=9675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/categories?post=9675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zleygroup.com\/fr\/wp-json\/wp\/v2\/tags?post=9675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}