{"id":9641,"date":"2026-07-22T15:26:36","date_gmt":"2026-07-22T07:26:36","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9641"},"modified":"2026-07-22T15:26:36","modified_gmt":"2026-07-22T07:26:36","slug":"pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/fr\/pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent\/","title":{"rendered":"\u00a0Principe actif de qualit\u00e9 pharmaceutique \u2013 Agent apaisant, anti-d\u00e9mangeaisons et antimicrobien"},"content":{"rendered":"

ZLEY\u00ae PAE \u2013 Paeonol (CAS 552-41-0):<\/strong><\/strong><\/h2>\n\n\n\n

 Principe actif de qualit\u00e9 pharmaceutique \u2013 Agent apaisant, anti-d\u00e9mangeaisons et antimicrobien<\/strong><\/strong><\/h2>\n\n\n\n
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Aper\u00e7u du produit<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE (Paeonol), also known as Peonol<\/strong> ou 2-hydroxy-4-methoxyacetophenone<\/strong>, is an active monomer compound extracted from the root bark of the peony plant (Paeonia suffruticosa) or the dried roots of Cynanchum paniculatum<\/a><\/a>. As a small-molecule phenolic compound, it offers a unique combination of antibacterial, anti-inflammatory, redness-reducing, and antioxidant benefits<\/a><\/a>.<\/p>\n\n\n\n

Paeonol has a long history of clinical use in China, with injectable formulations dating back to the 1970s. It is widely used in oral care, hair care, skincare, and cosmetic products<\/a><\/a>. Recent research has also highlighted its potential as an anti-acne adjuvant<\/strong>, with studies showing that it suppresses key inflammatory mediators, scavenges free radicals, and inhibits melanogenesis<\/a>.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Paeonol (CAS 552-41-0), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00ae PAE Product Information<\/strong><\/strong><\/h3>\n\n\n\n
Param\u00e8tre<\/td>Sp\u00e9cifications<\/td><\/tr>
Nom INCI<\/strong><\/td>Paeonol<\/td><\/tr>
Num\u00e9ro CAS<\/strong><\/td>552-41-0<\/td><\/tr>
Apparence<\/strong><\/td>Poudre cristalline blanche ou blanc cass\u00e9<\/td><\/tr>
Utilisation recommand\u00e9e<\/strong><\/td>0.01 \u2013 1.0%<\/td><\/tr>
Solubilit\u00e9<\/strong><\/td>Insoluble in water; soluble in ethanol and oils; soluble in propylene glycol with gentle heating<\/td><\/tr>
Principaux avantages<\/strong><\/td>Anti-inflammatory, antibacterial, antioxidant, redness reduction, anti-glycation<\/td><\/tr>
Traitement<\/strong><\/td>Dissolve in propylene glycol with gentle heating and add to formulation. Avoid prolonged heating.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00ae PAE Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes. Paeonol is listed in China’s Inventory of Existing Cosmetic Ingredients (2021 Edition) and is considered safe under normal, reasonable, and foreseeable conditions of use<\/a><\/a>. The following maximum historical use concentrations are established based on marketed products<\/a><\/a>:<\/p>\n\n\n\n

 <\/strong> <\/strong> <\/strong>Domaine d'application<\/strong><\/strong><\/td>Usage Type<\/strong><\/strong><\/td>Concentration maximale sans danger<\/strong><\/strong><\/td><\/tr>
Full body<\/strong><\/td>Leave-on<\/td>0.2%<\/td><\/tr>
Full body<\/strong><\/td>Rinse-off<\/td>0.3%<\/td><\/tr>
Face (incl. neck)<\/strong><\/td>Leave-on<\/td>0.3%<\/td><\/tr>
Eye area<\/strong><\/td>Leave-on<\/td>0.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Remarque :<\/strong> For rinse-off products, the same concentrations as leave-on apply for each corresponding area. For eye area products, additional eye irritation assessment is required<\/a>.<\/p>\n\n\n\n

M\u00e9canismes d'action<\/strong><\/strong><\/h3>\n\n\n\n
Avantage<\/strong><\/strong><\/td>M\u00e9canisme<\/strong><\/strong><\/td><\/tr>
Antibacterial<\/strong><\/td>Exhibits potent antibacterial activity against E. coli, S. aureus, and S. epidermidis with a MIC of 62.5 mg\/mL<\/a><\/a>. Recent research confirms efficacy against acne-associated bacteria including Cutibacterium acnes and S. aureus<\/a>.<\/td><\/tr>
Anti-inflammatoire<\/strong><\/td>Suppresses key inflammatory mediators, reducing erythema and swelling<\/a>. Has demonstrated therapeutic effects on acute skin eczema and pruritus<\/a><\/a>.<\/td><\/tr>
Antioxydant<\/strong><\/td>Scavenges oxygen free radicals, mitigates oxidative stress<\/a><\/a>.<\/td><\/tr>
Redness Reduction<\/strong><\/td>Calms irritated skin, reduces visible redness<\/a>.<\/td><\/tr>
Skin Brightening<\/strong><\/td>Inhibits tyrosinase activity to help even skin tone<\/a><\/a>.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Applications des produits<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE is a versatile skin conditioning agent suitable for a wide range of product categories:<\/p>\n\n\n\n

Cat\u00e9gorie de produits<\/strong><\/strong><\/td>Applications<\/strong><\/strong><\/td><\/tr>
Soins de la peau<\/strong><\/td>Masks, creams, serums for soothing, anti-itch, and redness-reducing effects<\/td><\/tr>
Hair & Body Care<\/strong><\/td>Shampoos, body washes, conditioners<\/td><\/tr>
Oral Care<\/strong><\/td>Toothpaste, mouthwash (unique natural cooling fragrance helps eliminate oral odor)<\/a><\/a><\/td><\/tr>
Conservation<\/strong><\/td>Plant-based antimicrobial agent and preservative booster<\/td><\/tr>
Acne Management<\/strong><\/td>Adjunctive skincare for anti-inflammatory and antibacterial support<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00ae PAE from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

Forte de plus de 20 ans d\u2019exp\u00e9rience dans ce domaine, ZLEY\u00ae s\u2019est d\u00e9velopp\u00e9e pour devenir une entreprise moderne alliant recherche, production, contr\u00f4le qualit\u00e9 et commercialisation. Nous nous engageons \u00e0 fournir des mati\u00e8res premi\u00e8res, des produits semi-finis et des solutions de formulation sur mesure de la plus haute qualit\u00e9 pour les soins personnels, afin de r\u00e9pondre aux besoins vari\u00e9s de nos clients. Notre r\u00e9seau de livraison mondial garantit un service fiable \u00e0 nos clients dans plus de 60 pays.<\/p>\n\n\n\n

Courriel :<\/strong> services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n

\u00c0 quel type d'assistance technique pouvez-vous vous attendre ?<\/strong><\/strong><\/h3>\n\n\n\n

En tant que fournisseur sp\u00e9cialis\u00e9, ZLEY\u00ae offre une valeur ajout\u00e9e qui va au-del\u00e0 du produit lui-m\u00eame :<\/p>\n\n\n\n