{"id":9730,"date":"2026-08-19T15:51:45","date_gmt":"2026-08-19T07:51:45","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9730"},"modified":"2026-08-19T15:51:45","modified_gmt":"2026-08-19T07:51:45","slug":"non-preservative-antimicrobial-synergist-for-mild-safe-formulations","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/es\/non-preservative-antimicrobial-synergist-for-mild-safe-formulations\/","title":{"rendered":"Sinergista antimicrobiano sin conservantes para formulaciones suaves y seguras"},"content":{"rendered":"<h2 class=\"wp-block-heading\"><strong>ZLEY\u00aeBIOCARE-PPD \u2013 Phenoxypropanediol (CAS 538-43-2): <\/strong><strong><\/strong><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Sinergista antimicrobiano sin conservantes para formulaciones suaves y seguras<\/strong><strong><\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"285\" src=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2.png\" alt=\"\" class=\"wp-image-9731\" title=\"\" srcset=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2.png 600w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-300x143.png 300w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-18x9.png 18w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-2-64x30.png 64w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption><\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Productos<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00aeBIOCARE-PPD (INCI: Phenoxypropanediol, chemical name: 3-Phenoxy-1,2-propanediol) is structurally similar to Chlorphenesin. However, it is&nbsp;<strong>not classified as a traditional preservative<\/strong>&nbsp;but rather as a&nbsp;<strong>synergistic antimicrobial booster<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phenoxypropanediol inhibits microbial growth by disrupting cell membranes, blocking the transport of cellular matrices in bacteria, and allowing the efflux of certain cellular components to impair normal bacterial metabolism.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a potent broad-spectrum antimicrobial agent, it is effective against Gram-positive bacteria, Gram-negative bacteria, molds, and yeasts. It helps reduce the amount of other preservatives needed in formulations, making it an ideal choice for&nbsp;<strong>preservative-free concepts<\/strong>&nbsp;y&nbsp;<strong>piel sensible<\/strong>&nbsp;applications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae is a professional supplier of Phenoxypropanediol (CAS 538-43-2), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ZLEY\u00aeBIOCARE-PPD Product Information<\/strong><strong><\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>Par\u00e1metro<\/td><td>Especificaci\u00f3n<\/td><\/tr><tr><td><strong>Denominaci\u00f3n INCI<\/strong><\/td><td>Fenoxipropanodiol<\/td><\/tr><tr><td><strong>N\u00famero CAS<\/strong><\/td><td>538-43-2<\/td><\/tr><tr><td><strong>Apariencia<\/strong><\/td><td>Cristales de color blanco a blanquecino<\/td><\/tr><tr><td><strong>Key Benefit<\/strong><\/td><td>Non-preservative antimicrobial synergist (reduces traditional preservative usage)<\/td><\/tr><tr><td><strong>Uso recomendado<\/strong><\/td><td>Face (incl. neck) \/ Leave-on: \u2264 0.5%<\/td><\/tr><tr><td><strong>Solubilidad<\/strong><\/td><td>Soluble in water and polyols at room temperature (e.g., 1,2-Pentanediol, 1,2-Hexanediol, Butylene Glycol, 1,3-Propanediol, etc.)<\/td><\/tr><tr><td><strong>Tratamiento<\/strong><\/td><td>Pre-dissolve in water or polyols, then add to the formulation and mix thoroughly<\/td><\/tr><tr><td><strong>Suitable Applications<\/strong><\/td><td>Transparent water-based systems, emulsions, facial cleansers, shampoos, wet wipes \u2013 both leave-on and rinse-off products<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Is ZLEY\u00aeBIOCARE-PPD Safe?<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>S\u00ed.<\/strong>&nbsp;It is permitted at&nbsp;<strong>\u22640.5%<\/strong>&nbsp;in leave-on facial (including neck) products. It is allowed in the EU, China, the USA, and other major markets.&nbsp;<strong>It is not listed as a preservative<\/strong>&nbsp;in regulatory positive lists, offering greater formulation flexibility.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Ventajas clave<\/strong><strong><\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Advantage<\/strong><strong><\/strong><\/td><td><strong>Descripci\u00f3n<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Safe &amp; Mild<\/strong><\/td><td>Excellent for sensitive skin and &#8220;preservative-free&#8221; concepts<\/td><\/tr><tr><td><strong>Broad-Spectrum Efficacy<\/strong><\/td><td>Effective against bacteria, molds, and yeasts<\/td><\/tr><tr><td><strong>Synergistic Booster<\/strong><\/td><td>Reduces the required amount of traditional preservatives<\/td><\/tr><tr><td><strong>Excellent Compatibility<\/strong><\/td><td>Works across multiple formulation types<\/td><\/tr><tr><td><strong>Good Stability<\/strong><\/td><td>Reliable performance under normal manufacturing conditions<\/td><\/tr><tr><td><strong>Cost-Effective<\/strong><\/td><td>Efficient at low usage levels<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Why Source ZLEY\u00aeBIOCARE-PPD from ZLEY\u00ae?<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">With over 20 years of integrated R&amp;D, production, quality control, and sales experience, ZLEY\u00ae is committed to providing premium personal care raw materials and customized solutions. Our global delivery network serves customers in over 60 countries.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u00bfQu\u00e9 tipo de asistencia t\u00e9cnica puedes esperar?<\/strong><strong><\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Soporte de formulaci\u00f3n:<\/strong>\u00a0Recomendaciones b\u00e1sicas sobre formulaci\u00f3n, sugerencias de combinaciones y orientaciones sobre el procesamiento<\/li>\n\n\n\n<li><strong>Consultor\u00eda Regulatoria:<\/strong>\u00a0Target market compliance assistance<\/li>\n\n\n\n<li><strong>Seguro de calidad:<\/strong>\u00a0Calidad constante, precios competitivos y una log\u00edstica global fiable<\/li>\n\n\n\n<li><strong>Informaci\u00f3n de mercado:<\/strong>\u00a0Latest trends and ingredient application insights<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Preguntas frecuentes (FAQ)<\/strong><strong><\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q1: Is Phenoxypropanediol a preservative?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: No. It is not listed as a preservative in regulatory positive lists (such as EU Annex V). It functions as a&nbsp;<strong>synergistic antimicrobial booster<\/strong>&nbsp;that enhances preservation systems while reducing the need for traditional preservatives.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q2: What is the recommended usage level?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">R: El nivel de uso recomendado es&nbsp;<strong>\u2264<\/strong><strong>&nbsp;<\/strong><strong>0.5%<\/strong>&nbsp;in leave-on facial (including neck) products. This concentration is compliant with EU, US, and Chinese regulations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q3: How does Phenoxypropanediol work?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It disrupts microbial cell membranes, blocks cellular matrix transport, and impairs normal bacterial metabolism, effectively inhibiting bacterial, mold, and yeast growth.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q4: What types of products is it suitable for?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It is suitable for transparent water-based systems, emulsions, facial cleansers, shampoos, and wet wipes, for both leave-on and rinse-off applications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q5: How can I request samples and technical documentation?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Please contact our export team:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Correo electr\u00f3nico:<\/strong>&nbsp;<a href=\"mailto:services@zleygroup.com\"><u>services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Include your company details, target product type, and target market for the most relevant information.<\/p>","protected":false},"excerpt":{"rendered":"<p>ZLEY\u00aeBIOCARE-PPD \u2013 Phenoxypropanediol (CAS 538-43-2): Non-Preservative Antimicrobial Synergist for Mild, Safe Formulations Product Overview ZLEY\u00aeBIOCARE-PPD (INCI: Phenoxypropanediol, chemical name: 3-Phenoxy-1,2-propanediol) [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9731,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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