{"id":9675,"date":"2026-08-05T16:22:18","date_gmt":"2026-08-05T08:22:18","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9675"},"modified":"2026-08-05T16:22:18","modified_gmt":"2026-08-05T08:22:18","slug":"liposome-targeted-delivery-targets-melanocyte-stem-cells-long-term-sustained-release-gentle-brightening-spot-correction","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/es\/liposome-targeted-delivery-targets-melanocyte-stem-cells-long-term-sustained-release-gentle-brightening-spot-correction\/","title":{"rendered":"Administraci\u00f3n dirigida mediante liposomas; act\u00faa sobre las c\u00e9lulas madre de los melanocitos, liberaci\u00f3n prolongada y sostenida, aclarado suave y correcci\u00f3n de manchas"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>ZLEY\u00ae577PRO \u2013 4-Butylresorcinol Liposome-135: <\/strong><strong><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Administraci\u00f3n dirigida mediante liposomas; act\u00faa sobre las c\u00e9lulas madre de los melanocitos, liberaci\u00f3n prolongada y sostenida, aclarado suave y correcci\u00f3n de manchas<\/strong><strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"702\" height=\"575\" src=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472.png\" alt=\"\" class=\"wp-image-9676\" title=\"\" srcset=\"https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472.png 702w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-300x246.png 300w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-15x12.png 15w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-600x491.png 600w, https:\/\/www.zleygroup.com\/wp-content\/uploads\/2026\/08\/\u56fe\u72472-64x52.png 64w\" sizes=\"(max-width: 702px) 100vw, 702px\" \/><figcaption><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Productos<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae577PRO (4-Butylresorcinol Liposome-135) features&nbsp;<strong>liposome<\/strong><strong>\u2013<\/strong><strong>targeted delivery technology<\/strong>&nbsp;that protects the brightening active &#8220;577&#8221; (4-Butylresorcinol) and delivers it directly to the basal layer of the skin. The system provides&nbsp;<strong>sustained release<\/strong>&nbsp;of 577, targeting melanocyte stem cells and acting at both melanin synthesis and post\u2011synthesis stages to synergistically inhibit melanin production, fade surface pigmentation, and deliver gentle brightening and spot\u2011correcting effects.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ZLEY\u00ae is a professional supplier of 4-Butylresorcinol Liposome-135 (CAS: 7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>ZLEY\u00ae577PRO Product Information<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Par\u00e1metro<\/strong><strong><\/strong><\/td><td><strong>Especificaci\u00f3n<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Denominaci\u00f3n INCI<\/strong><\/td><td>Water, PEG-40 Hydrogenated Castor Oil, Butylene Glycol, 4-Butylresorcinol, Lecithin, 1,2-Hexanediol, Tocopheryl Acetate<\/td><\/tr><tr><td><strong>N\u00fameros CAS<\/strong><\/td><td>7732-18-5, 61788-85-0, 107-88-0, 18979-61-8, 8002-43-5, 6920-22-5, 58-95-7<\/td><\/tr><tr><td><strong>Apariencia<\/strong><\/td><td>Yellow to dark yellow liquid, characteristic odor<\/td><\/tr><tr><td><strong>Active Content (4-Butylresorcinol)<\/strong><\/td><td>12 \u2013 15%<\/td><\/tr><tr><td><strong>Uso recomendado<\/strong><\/td><td>1 \u2013 10%<\/td><\/tr><tr><td><strong>Solubilidad<\/strong><\/td><td>Alcohol-soluble, water-dispersible<\/td><\/tr><tr><td><strong>Recommended Formulation pH<\/strong><\/td><td>4.5 \u2013 6.0<\/td><\/tr><tr><td><strong>Beneficios clave<\/strong><\/td><td>Brightening &amp; spot correction, antioxidant &amp; radiance enhancement<\/td><\/tr><tr><td><strong>Nota sobre el almacenamiento<\/strong><\/td><td>Protect from high temperatures and light<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Is ZLEY\u00ae577PRO Safe?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Yes. ZLEY\u00ae577PRO is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following maximum concentrations:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Tipo de producto<\/strong><strong><\/strong><\/td><td><strong>Concentraci\u00f3n m\u00e1xima segura<\/strong><strong><\/strong><\/td><\/tr><tr><td><strong>Facial toners<\/strong><\/td><td>\u2264 4.3%<\/td><\/tr><tr><td><strong>Emulsions \/ Lotions<\/strong><\/td><td>\u2264 9.0%<\/td><\/tr><tr><td><strong>Cremas faciales<\/strong><\/td><td>\u2264 15.6%<\/td><\/tr><tr><td><strong>Serums \/ Essences<\/strong><\/td><td>\u2264 18.3%<\/td><\/tr><tr><td><strong>Body creams \/ lotions<\/strong><\/td><td>\u2264 1.6%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">At these concentrations, it does not pose a risk to human health.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Aplicaciones de los productos<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In cosmetics and skincare, ZLEY\u00ae577PRO functions primarily as a&nbsp;<strong>agente acondicionador de la piel<\/strong>. It is suitable for emulsions, creams, gels, and water-based formulations, making it ideal for brightening and spot-correcting products.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Filosof\u00eda de desarrollo de productos<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To address the three major challenges of 4-Butylresorcinol (&#8220;577&#8221;) \u2013&nbsp;<strong>strong irritation, low stability, and poor water solubility<\/strong>&nbsp;\u2013 ZLEY\u00ae&#8217;s R&amp;D team developed ZLEY\u00ae577PRO. Using liposome-targeted delivery technology, it protects the active ingredient &#8220;577&#8221; during delivery to the basal layer, provides long-term sustained release, targets melanocyte stem cells, inhibits melanin production, fades surface pigmentation, and delivers gentle brightening and spot-correcting efficacy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why Source ZLEY\u00ae577PRO from ZLEY\u00ae?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">With over 20 years of dedicated experience, ZLEY\u00ae has evolved into a modern enterprise integrating R&amp;D, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Correo electr\u00f3nico:<\/strong>&nbsp;<a href=\"mailto:services@zleygroup.com\"><u>services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u00bfQu\u00e9 tipo de asistencia t\u00e9cnica puedes esperar?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Como proveedor especializado, ZLEY\u00ae ofrece un valor que va m\u00e1s all\u00e1 del propio producto:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Soporte de formulaci\u00f3n:<\/strong>\u00a0Recomendaciones b\u00e1sicas sobre formulaci\u00f3n, sugerencias de combinaciones y orientaciones sobre el procesamiento<\/li>\n\n\n\n<li><strong>Consultor\u00eda Regulatoria:<\/strong>\u00a0Asistencia en la interpretaci\u00f3n de los requisitos de cumplimiento normativo de los mercados objetivo<\/li>\n\n\n\n<li><strong>Seguro de calidad:<\/strong>\u00a0Consistent product quality, competitive pricing, and reliable global logistics<\/li>\n\n\n\n<li><strong>Informaci\u00f3n de mercado:<\/strong>\u00a0\u00daltimas tendencias del mercado y an\u00e1lisis sobre el uso de ingredientes<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Preguntas frecuentes (FAQ)<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>1<\/strong><strong>: How does the liposome delivery system work?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: The liposome system encapsulates 4-Butylresorcinol within lipid bilayers, protecting it from degradation and enabling efficient transport across the stratum corneum. It delivers the active directly to the basal layer where melanocyte stem cells reside, and releases it gradually over time for sustained brightening efficacy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>2<\/strong><strong>: What is the recommended usage level for ZLEY\u00ae577PRO?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">R: El rango de uso recomendado es&nbsp;<strong>1\u201310%<\/strong>&nbsp;depending on product type and desired efficacy. Specific safe maximums by product category apply (see Safety section above).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>3<\/strong><strong>: Is ZLEY\u00ae577PRO suitable for sensitive skin?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: Yes. The liposome encapsulation provides controlled, sustained release of the active ingredient, significantly reducing the irritation potential compared to unencapsulated 4-Butylresorcinol. This makes it suitable for sensitive skin formulations.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Q<\/strong><strong>4<\/strong><strong>: What skin concerns does ZLEY\u00ae577PRO address?<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A: It addresses hyperpigmentation concerns including melasma, sun spots, age spots, post-inflammatory hyperpigmentation (PIH), and&nbsp;uneven skin tone, while also providing antioxidant and radiance-enhancing benefits.<\/p>","protected":false},"excerpt":{"rendered":"<p>ZLEY\u00ae577PRO \u2013 4-Butylresorcinol Liposome-135: Liposome Targeted Delivery; Targets Melanocyte Stem Cells, Long-Term Sustained Release, Gentle Brightening &amp; Spot Correction Product [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9676,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[69],"tags":[],"class_list":["post-9675","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-active-ingredients"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/posts\/9675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/comments?post=9675"}],"version-history":[{"count":0,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/posts\/9675\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/media\/9676"}],"wp:attachment":[{"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/media?parent=9675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/categories?post=9675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zleygroup.com\/es\/wp-json\/wp\/v2\/tags?post=9675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}