ZLEY® RA – Resorcinol Acetate (CAS 102-29-4):
Producto de venta libre aprobado por la FDA para combatir el acné
Productos
ZLEY® RA (INCI: Resorcinol Acetate), also known as Acetylresorcinol o Euresol, is a resorcinol derivative. It is recognized by the U.S. FDA as an approved active ingredient in over-the-counter (OTC) topical acne drug products and is listed in the U.S. OTC Drug Monograph for acne treatment. It offers antibacterial, post-acne spot-fading, and keratolytic properties. It is used to treat acne, seborrheic dermatitis, and tinea pedis, and is also effective as a mild, non-irritating anti-dandruff agent for the scalp.
ZLEY® is a professional supplier of Resorcinol Acetate (CAS 102-29-4), providing stable quality, technical support, and global delivery covering over 60 countries.
ZLEY® RA Product Information
| Parámetro | Especificación |
| Denominación INCI | Acetato de resorcinol |
| Número CAS | 102-29-4 |
| Apariencia | Colorless to pale yellow viscous liquid, characteristic odor |
| Uso recomendado | 0.1 – 1.0% [Note: Up to 3% in the U.S. and Canada under OTC drug rules] |
| Solubilidad | Insoluble in water; soluble in alcohol and oils |
| Formulaciones adecuadas | Anti-acne products, anti-dandruff products |
| Tratamiento | Emulsion systems: Add at low temperature after emulsification and mix thoroughly. Anhydrous oil systems: Add directly to the oil phase and dissolve. |
| Thickener Compatibility | Suitable for ion-tolerant systems. |
| Indicaciones de conservación | Avoid prolonged heating; store in light-protected conditions. |
Is ZLEY® RA Safe?
Yes. According to the U.S. FDA OTC Drug Monograph, Resorcinol Monoacetate (3%) is recognized as safe and effective (GRASE) for use in over-the-counter topical acne drug products when formulated according to established conditions . Safety assessments based on China’s “Information on the Use of Ingredients in Marketed Products” confirm that up to 1% in leave-on products is safe .
Aplicaciones de los productos
In cosmetics and skincare, ZLEY® RA functions primarily as a agente acondicionador de la piel. Its key applications include
- Anti-acne products – Reduces blemishes, pimples, and blackheads
- Anti-dandruff products – Mild, non-irritating scalp treatment
- Seborrheic dermatitis treatments
- Tinea pedis (athlete’s foot) treatments
Why Source ZLEY® RA from ZLEY®?
Con más de 20 años de experiencia dedicada, ZLEY® se ha convertido en una empresa moderna que integra investigación, producción, control de calidad y ventas. Nos comprometemos a ofrecer materias primas para el cuidado personal, productos semiacabados y soluciones de formulación a medida de la máxima calidad para satisfacer las diversas necesidades de nuestros clientes. Nuestra red de distribución global garantiza un servicio fiable a clientes de más de 60 países.
Correo electrónico: [email protected]
¿Qué tipo de asistencia técnica puedes esperar?
Como proveedor especializado, ZLEY® ofrece un valor que va más allá del propio producto:
- Soporte de formulación: Recomendaciones básicas sobre formulación, sugerencias de combinaciones y orientaciones sobre el procesamiento
- Consultoría Regulatoria: Assistance with interpreting compliance requirements for target markets (U.S. OTC Monograph, EU regulations, etc.)
- Seguro de calidad: Calidad constante, precios competitivos y una logística global fiable
- Información de mercado: Últimas tendencias del mercado y análisis sobre el uso de ingredientes
ZLEY® RA – Frequently Asked Questions (FAQ)
Q1: What is the FDA status of Resorcinol Acetate?
A: Resorcinol Acetate is listed as a Category I (GRASE – Generally Recognized as Safe and Effective) active ingredient for OTC topical acne drug products in the U.S. FDA regulations (21 CFR § 333.310). The monograph permits up to 3% Resorcinol Monoacetate (chemically equivalent to Resorcinol Acetate) in OTC acne products. It is also included in China’s “Inventory of Existing Cosmetic Ingredients (2021 Edition)”.
Q2: How does Resorcinol Acetate differ from Resorcinol?
A: Resorcinol Acetate is the esterified (acetylated) form of resorcinol. This structural modification reduces reactivity and irritation potential while maintaining effective acne-fighting properties, making it more suitable for controlled formulation use. Resorcinol itself is regulated in the EU for hair dye applications and cannot be used in leave-on cosmetics.
Q3: What are the regulatory concentration limits for different markets?
A:The concentration limits vary by market:
- U.S. (OTC Drug): Up to 3%
- Canada: Up to 3% (permitted in OTC acne products).
- China (Cosmetics): Maximum historical use in leave-on products is 1% based on marketed product data.
- UE: Resorcinol Acetate is not specifically listed in Annex V; formulators should verify compliance on a product-by-product basis
Q4: Is ZLEY® RA suitable for sensitive skin?
A: Resorcinol Acetate is generally considered milder than free resorcinol due to its esterified structure. However, individual skin tolerance may vary. For sensitive skin formulations, we recommend starting at lower concentrations (0.1–0.5%) and conducting patch testing. As with all OTC drug ingredients in the U.S., appropriate warnings and directions must be included on product labeling.