{"id":9641,"date":"2026-07-22T15:26:36","date_gmt":"2026-07-22T07:26:36","guid":{"rendered":"https:\/\/www.zleygroup.com\/?p=9641"},"modified":"2026-07-22T15:26:36","modified_gmt":"2026-07-22T07:26:36","slug":"pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent","status":"publish","type":"post","link":"https:\/\/www.zleygroup.com\/de\/pharmaceutical-grade-active-soothing-anti-itch-antimicrobial-agent\/","title":{"rendered":"\u00a0Wirkstoff in pharmazeutischer Qualit\u00e4t \u2013 beruhigend, juckreizstillend, antimikrobiell"},"content":{"rendered":"

ZLEY\u00ae PAE \u2013 Paeonol (CAS 552-41-0):<\/strong><\/strong><\/h2>\n\n\n\n

 Wirkstoff in pharmazeutischer Qualit\u00e4t \u2013 beruhigend, juckreizstillend, antimikrobiell<\/strong><\/strong><\/h2>\n\n\n\n
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Produkt\u00fcbersicht<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE (Paeonol), also known as Peonol<\/strong> oder 2-hydroxy-4-methoxyacetophenone<\/strong>, is an active monomer compound extracted from the root bark of the peony plant (Paeonia suffruticosa) or the dried roots of Cynanchum paniculatum<\/a><\/a>. As a small-molecule phenolic compound, it offers a unique combination of antibacterial, anti-inflammatory, redness-reducing, and antioxidant benefits<\/a><\/a>.<\/p>\n\n\n\n

Paeonol has a long history of clinical use in China, with injectable formulations dating back to the 1970s. It is widely used in oral care, hair care, skincare, and cosmetic products<\/a><\/a>. Recent research has also highlighted its potential as an anti-acne adjuvant<\/strong>, with studies showing that it suppresses key inflammatory mediators, scavenges free radicals, and inhibits melanogenesis<\/a>.<\/p>\n\n\n\n

ZLEY\u00ae is a professional supplier of Paeonol (CAS 552-41-0), providing stable quality, technical support, and global delivery covering over 60 countries.<\/p>\n\n\n\n

ZLEY\u00ae PAE Product Information<\/strong><\/strong><\/h3>\n\n\n\n
Parameter<\/td>Spezifikation<\/td><\/tr>
INCI-Name<\/strong><\/td>Paeonol<\/td><\/tr>
CAS-Nummer<\/strong><\/td>552-41-0<\/td><\/tr>
Aussehen<\/strong><\/td>Wei\u00dfes oder cremefarbenes kristallines Pulver<\/td><\/tr>
Empfohlener Verwendungszweck<\/strong><\/td>0.01 \u2013 1.0%<\/td><\/tr>
L\u00f6slichkeit<\/strong><\/td>Insoluble in water; soluble in ethanol and oils; soluble in propylene glycol with gentle heating<\/td><\/tr>
Hauptvorteile<\/strong><\/td>Anti-inflammatory, antibacterial, antioxidant, redness reduction, anti-glycation<\/td><\/tr>
Verarbeitung<\/strong><\/td>Dissolve in propylene glycol with gentle heating and add to formulation. Avoid prolonged heating.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Is ZLEY\u00ae PAE Safe?<\/strong><\/strong><\/h3>\n\n\n\n

Yes. Paeonol is listed in China’s Inventory of Existing Cosmetic Ingredients (2021 Edition) and is considered safe under normal, reasonable, and foreseeable conditions of use<\/a><\/a>. The following maximum historical use concentrations are established based on marketed products<\/a><\/a>:<\/p>\n\n\n\n

 <\/strong> <\/strong> <\/strong>Anwendungsbereich<\/strong><\/strong><\/td>Usage Type<\/strong><\/strong><\/td>Maximale sichere Konzentration<\/strong><\/strong><\/td><\/tr>
Full body<\/strong><\/td>Leave-on<\/td>0.2%<\/td><\/tr>
Full body<\/strong><\/td>Rinse-off<\/td>0.3%<\/td><\/tr>
Face (incl. neck)<\/strong><\/td>Leave-on<\/td>0.3%<\/td><\/tr>
Eye area<\/strong><\/td>Leave-on<\/td>0.01%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Hinweis:<\/strong> For rinse-off products, the same concentrations as leave-on apply for each corresponding area. For eye area products, additional eye irritation assessment is required<\/a>.<\/p>\n\n\n\n

Wirkmechanismen<\/strong><\/strong><\/h3>\n\n\n\n
Nutzen<\/strong><\/strong><\/td>Mechanismus<\/strong><\/strong><\/td><\/tr>
Antibacterial<\/strong><\/td>Exhibits potent antibacterial activity against E. coli, S. aureus, and S. epidermidis with a MIC of 62.5 mg\/mL<\/a><\/a>. Recent research confirms efficacy against acne-associated bacteria including Cutibacterium acnes and S. aureus<\/a>.<\/td><\/tr>
Entz\u00fcndungshemmend<\/strong><\/td>Suppresses key inflammatory mediators, reducing erythema and swelling<\/a>. Has demonstrated therapeutic effects on acute skin eczema and pruritus<\/a><\/a>.<\/td><\/tr>
Antioxidans<\/strong><\/td>Scavenges oxygen free radicals, mitigates oxidative stress<\/a><\/a>.<\/td><\/tr>
Redness Reduction<\/strong><\/td>Calms irritated skin, reduces visible redness<\/a>.<\/td><\/tr>
Skin Brightening<\/strong><\/td>Inhibits tyrosinase activity to help even skin tone<\/a><\/a>.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Produktanwendungen<\/strong><\/strong><\/h3>\n\n\n\n

ZLEY\u00ae PAE is a versatile skin conditioning agent suitable for a wide range of product categories:<\/p>\n\n\n\n

Produktkategorie<\/strong><\/strong><\/td>Anwendungen<\/strong><\/strong><\/td><\/tr>
Hautpflege<\/strong><\/td>Masks, creams, serums for soothing, anti-itch, and redness-reducing effects<\/td><\/tr>
Hair & Body Care<\/strong><\/td>Shampoos, body washes, conditioners<\/td><\/tr>
Oral Care<\/strong><\/td>Toothpaste, mouthwash (unique natural cooling fragrance helps eliminate oral odor)<\/a><\/a><\/td><\/tr>
Erhaltung<\/strong><\/td>Plant-based antimicrobial agent and preservative booster<\/td><\/tr>
Acne Management<\/strong><\/td>Adjunctive skincare for anti-inflammatory and antibacterial support<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Why Source ZLEY\u00ae PAE from ZLEY\u00ae?<\/strong><\/strong><\/h3>\n\n\n\n

Mit \u00fcber 20 Jahren Erfahrung in diesem Bereich hat sich ZLEY\u00ae zu einem modernen Unternehmen entwickelt, das Forschung, Produktion, Qualit\u00e4tskontrolle und Vertrieb unter einem Dach vereint. Wir haben es uns zur Aufgabe gemacht, Rohstoffe, Halbfertigprodukte und ma\u00dfgeschneiderte Rezepturl\u00f6sungen f\u00fcr die K\u00f6rperpflege von h\u00f6chster Qualit\u00e4t anzubieten, um den vielf\u00e4ltigen Bed\u00fcrfnissen unserer Kunden gerecht zu werden. Unser globales Liefernetzwerk gew\u00e4hrleistet einen zuverl\u00e4ssigen Service f\u00fcr Kunden in \u00fcber 60 L\u00e4ndern.<\/p>\n\n\n\n

E-Mail:<\/strong> services@zleygroup.com<\/u><\/a><\/p>\n\n\n\n

Welchen technischen Support k\u00f6nnen Sie erwarten?<\/strong><\/strong><\/h3>\n\n\n\n

Als spezialisierter Anbieter bietet ZLEY\u00ae einen Mehrwert, der \u00fcber das Produkt selbst hinausgeht:<\/p>\n\n\n\n