Der “Experte für punktuelle Entsorgung”

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ZLEY®UP – Undecylenoyl Phenylalanine (CAS 175357-18-3):

Der “Experte für punktuelle Entsorgung”

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The "Spot Disposal Expert" 3

ZLEY®UP (INCI: Undecylenoyl Phenylalanine), also known as Sepiwhite, is a premium skin-brightening agent used in high‑end brightening and spot‑correcting products such as SK-II and OLAY.

As a structural analog of α-melanocyte-stimulating hormone (α-MSH), Undecylenoyl Phenylalanine competitively binds to MC1-R receptors on melanocytes, effectively blocking the cAMP/PKA signaling pathway. This action reduces the expression of key melanogenic enzymes and directly inhibits tyrosinase activity, thereby significantly decreasing melanin production for visible brightening and spot-fading results.

ZLEY® is a professional supplier of Undecylenoyl Phenylalanine (CAS 175357-18-3), providing stable quality, technical support, and global delivery covering over 60 countries.

ZLEY®UP Product Information

ParameterSpezifikation
INCI-NameUndecylenoylphenylalanin
CAS-Nummer175357-18-3
AussehenWhite to off-white powder, characteristic odor
Empfohlener Verwendungszweck0,1 - 2,0%
LöslichkeitÖllöslich
VerarbeitungAdd directly to the oil phase with heating to dissolve
Key BenefitBrightening & spot correction
Mechanismusα-MSH antagonist; competitively binds to MC1-R; inhibits cAMP/PKA melanogenic signaling pathway

Is ZLEY®UP Safe?

Yes. ZLEY®UP is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at concentrations bis zu 2,0% in both leave-on and rinse-off products (for rinse-off, the same limit applies by referencing leave-on usage data).

Produktanwendungen

In cosmetics and skincare, ZLEY®UP functions primarily as a Hautpflegemittel. Its lipid-amino acid structure provides excellent skin affinity, making it suitable for sensitive skin in brightening, spot-correcting, and antioxidant formulations, as well as compound liposome development. It has become a benchmark ingredient in efficacy-driven skincare. By combining it with niacinamide, adenosine, and other actives, formulators can build full-pathway brightening systems that deliver both safety and high performance, continuously empowering brands.

Why Source ZLEY®UP from ZLEY®?

With over 20 years of dedicated experience, ZLEY® has evolved into a modern enterprise integrating R&D, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.

E-Mail: [email protected]

Welchen technischen Support können Sie erwarten?

Als spezialisierter Anbieter bietet ZLEY® einen Mehrwert, der über das Produkt selbst hinausgeht:

  • Unterstützung bei der Formulierung: Grundlegende Empfehlungen zur Rezeptur, Kombinationsvorschläge und Hinweise zur Verarbeitung
  • Regulierungsberatung: Unterstützung bei der Auslegung von Compliance-Anforderungen für Zielmärkte
  • Qualitätssicherung: Consistent product quality, competitive pricing, and reliable global logistics
  • Marktinformationen: Aktuelle Markttrends und Einblicke in die Anwendung von Inhaltsstoffen

Häufig gestellte Fragen (FAQ)

Q1: How does ZLEY®UP work for brightening and spot correction?

A: ZLEY®UP is a structural analog of α-MSH. It competitively binds to MC1-R receptors on melanocytes, blocking the cAMP/PKA signaling pathway and reducing the production of melanogenic enzymes. It also directly inhibits tyrosinase activity, providing a dual-action approach to reducing melanin and fading dark spots.

Q2: Is ZLEY®UP suitable for sensitive skin?

A: Yes. Its lipid-amino acid structure gives it excellent skin affinity and mildness, making it highly suitable for sensitive skin formulations.

Q3: What is the recommended usage level?

A: The recommended usage range is 0.1%–2.0%. Safety assessments confirm it is safe up to 2.0% in leave-on products.

Q4: Can ZLEY®UP be combined with other brightening ingredients?

A: Yes. It shows strong synergy with niacinamide, adenosine, phenylethyl resorcinol, tranexamic acid, and other brightening actives to build comprehensive, full-pathway brightening systems.