ZLEY® RA – Resorcinol Acetate (CAS 102-29-4):
Von der FDA zugelassenes rezeptfreies Mittel gegen Akne
Produktübersicht
ZLEY® RA (INCI: Resorcinol Acetate), also known as Acetylresorcinol oder Euresol, is a resorcinol derivative. It is recognized by the U.S. FDA as an approved active ingredient in over-the-counter (OTC) topical acne drug products and is listed in the U.S. OTC Drug Monograph for acne treatment. It offers antibacterial, post-acne spot-fading, and keratolytic properties. It is used to treat acne, seborrheic dermatitis, and tinea pedis, and is also effective as a mild, non-irritating anti-dandruff agent for the scalp.
ZLEY® is a professional supplier of Resorcinol Acetate (CAS 102-29-4), providing stable quality, technical support, and global delivery covering over 60 countries.
ZLEY® RA Product Information
| Parameter | Spezifikation |
| INCI-Name | Resorcinacetat |
| CAS-Nummer | 102-29-4 |
| Aussehen | Colorless to pale yellow viscous liquid, characteristic odor |
| Empfohlener Verwendungszweck | 0.1 – 1.0% [Note: Up to 3% in the U.S. and Canada under OTC drug rules] |
| Löslichkeit | Insoluble in water; soluble in alcohol and oils |
| Geeignete Formulierungen | Anti-acne products, anti-dandruff products |
| Verarbeitung | Emulsion systems: Nach der Emulgierung bei niedriger Temperatur hinzufügen und gründlich vermischen. Anhydrous oil systems: Add directly to the oil phase and dissolve. |
| Thickener Compatibility | Suitable for ion-tolerant systems. |
| Lagerungshinweise | Avoid prolonged heating; store in light-protected conditions. |
Is ZLEY® RA Safe?
Yes. According to the U.S. FDA OTC Drug Monograph, Resorcinol Monoacetate (3%) is recognized as safe and effective (GRASE) for use in over-the-counter topical acne drug products when formulated according to established conditions . Safety assessments based on China’s “Information on the Use of Ingredients in Marketed Products” confirm that up to 1% in leave-on products is safe .
Produktanwendungen
In cosmetics and skincare, ZLEY® RA functions primarily as a Hautpflegemittel. Its key applications include
- Anti-acne products – Reduces blemishes, pimples, and blackheads
- Anti-dandruff products – Mild, non-irritating scalp treatment
- Seborrheic dermatitis treatments
- Tinea pedis (athlete’s foot) treatments
Why Source ZLEY® RA from ZLEY®?
Mit über 20 Jahren Erfahrung in diesem Bereich hat sich ZLEY® zu einem modernen Unternehmen entwickelt, das Forschung, Produktion, Qualitätskontrolle und Vertrieb unter einem Dach vereint. Wir haben es uns zur Aufgabe gemacht, Rohstoffe, Halbfertigprodukte und maßgeschneiderte Rezepturlösungen für die Körperpflege von höchster Qualität anzubieten, um den vielfältigen Bedürfnissen unserer Kunden gerecht zu werden. Unser globales Liefernetzwerk gewährleistet einen zuverlässigen Service für Kunden in über 60 Ländern.
E-Mail: [email protected]
Welchen technischen Support können Sie erwarten?
Als spezialisierter Anbieter bietet ZLEY® einen Mehrwert, der über das Produkt selbst hinausgeht:
- Unterstützung bei der Formulierung: Grundlegende Empfehlungen zur Rezeptur, Kombinationsvorschläge und Hinweise zur Verarbeitung
- Regulierungsberatung: Assistance with interpreting compliance requirements for target markets (U.S. OTC Monograph, EU regulations, etc.)
- Qualitätssicherung: Gleichbleibende Qualität, wettbewerbsfähige Preise und zuverlässige weltweite Logistik
- Marktinformationen: Aktuelle Markttrends und Einblicke in die Anwendung von Inhaltsstoffen
ZLEY® RA – Frequently Asked Questions (FAQ)
Q1: What is the FDA status of Resorcinol Acetate?
A: Resorcinol Acetate is listed as a Category I (GRASE – Generally Recognized as Safe and Effective) active ingredient for OTC topical acne drug products in the U.S. FDA regulations (21 CFR § 333.310). The monograph permits up to 3% Resorcinol Monoacetate (chemically equivalent to Resorcinol Acetate) in OTC acne products. It is also included in China’s “Inventory of Existing Cosmetic Ingredients (2021 Edition)”.
Q2: How does Resorcinol Acetate differ from Resorcinol?
A: Resorcinol Acetate is the esterified (acetylated) form of resorcinol. This structural modification reduces reactivity and irritation potential while maintaining effective acne-fighting properties, making it more suitable for controlled formulation use. Resorcinol itself is regulated in the EU for hair dye applications and cannot be used in leave-on cosmetics.
Q3: What are the regulatory concentration limits for different markets?
A:The concentration limits vary by market:
- U.S. (OTC Drug): Up to 3%
- Canada: Up to 3% (permitted in OTC acne products).
- China (Cosmetics): Maximum historical use in leave-on products is 1% based on marketed product data.
- EU: Resorcinol Acetate is not specifically listed in Annex V; formulators should verify compliance on a product-by-product basis
Q4: Is ZLEY® RA suitable for sensitive skin?
A: Resorcinol Acetate is generally considered milder than free resorcinol due to its esterified structure. However, individual skin tolerance may vary. For sensitive skin formulations, we recommend starting at lower concentrations (0.1–0.5%) and conducting patch testing. As with all OTC drug ingredients in the U.S., appropriate warnings and directions must be included on product labeling.