ZLEY® UG – Undecenoyl Glycine (CAS 54301-26-7):
A Multifunctional Skin Conditioner for Sebum Control, Antimicrobial Action, and Preservation Boosting

Product Overview
ZLEY® UG (Undecenoyl Glycine) is a multifunctional skin conditioning agent derived from the combination of undecylenic acid (a natural fatty acid) and glycine. It offers a unique balance of sebum regulation, antimicrobial activity, and preservation enhancement, making it a versatile ingredient for modern personal care formulations.
Key benefits include:
Sebum Control & Antimicrobial: Inhibits 5-alpha reductase to regulate sebum secretion, and significantly suppresses Cutibacterium acnes.
Anti-Dandruff & Deodorant: Effectively targets Malassezia yeasts (associated with dandruff) and provides 24-hour deodorant efficacy.
Preservation Booster: Enhances the activity of traditional preservatives against bacteria and mold, enabling milder preservation systems suitable for sensitive skin.
ZLEY® is a professional supplier of Undecenoyl Glycine (CAS 54301-26-7), providing stable quality, technical support, and global delivery covering over 60 countries.
ZLEY® UG Product Information
| Parameter | Specification |
| INCI Name | Undecenoyl Glycine |
| CAS Number | 54301-26-7 |
| Appearance | White to off-white powder |
| Recommended Usage | 0.1% – 0.5% |
| Solubility | Soluble in alcohol; practically insoluble in water |
| Processing | Pre-dissolve in an appropriate solvent (e.g., propylene glycol) with gentle heating before adding to formulation. Avoid prolonged heating. |
| Key Benefits | Sebum control, antimicrobial, anti-dandruff, deodorant, preservation booster |
Is ZLEY® UG Safe?
Yes. The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Undecenoyl Glycine is safe for use in cosmetic products at concentrations up to 0.3% in leave-on formulations (when the formulation is non-irritating). It is considered safe for use in rinse-off formulations as well. Additionally, based on data from the China National Institutes for Food and Drug Control (NIFDC) International Cosmetic Safety Assessment Data Index, Undecenoyl Glycine is used at a concentration of 0.5% in full-body leave-on products. For rinse-off products, the same concentration (0.5%) is considered safe by referencing the leave-on usage data.
Under normal, reasonable, and foreseeable conditions of use at these levels, ZLEY® UG does not pose a risk to human health.
Product Applications
ZLEY® UG is a versatile skin conditioning agent suitable for a wide range of product types:
| Product Category | Examples |
| Hair Care | Shampoos (oil control, anti-dandruff) |
| Skincare | Anti-acne serums, sensitive skin cleansers |
| Deodorants | Antiperspirants, body sprays |
| Baby Care | Gentle body washes (mild and non-irritating) |
| Preservation Systems | Mild preservation booster in combination with traditional preservatives |
Why Source ZLEY® UG from ZLEY®?
With over 20 years of dedicated experience, ZLEY® has evolved into a modern enterprise integrating research, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions to meet diverse customer needs. Our global delivery network ensures reliable service to customers in over 60 countries.
Email: [email protected]
What Technical Support Can You Expect?
As a specialized supplier, ZLEY® offers value beyond the product itself:
- Formulation Support: Basic formulation recommendations, combination suggestions, and processing guidance
- Regulatory Consulting: Assistance with interpreting compliance requirements for target markets
- Quality Assurance: Consistent quality, competitive pricing, and reliable global logistics
- Market Intelligence: Latest market trends and ingredient application insights
ZLEY® UG – Frequently Asked Questions (FAQ)
Q1: How does ZLEY® UG control sebum and acne?
A: ZLEY® UG works by inhibiting 5-alpha reductase, the enzyme responsible for converting testosterone into dihydrotestosterone (DHT), which stimulates sebaceous gland activity and sebum overproduction. By reducing sebum secretion, it helps prevent clogged pores and Cutibacterium acnes overgrowth that lead to acne. Its direct antimicrobial activity further enhances its efficacy against acne-causing bacteria.
Q2: How does ZLEY® UG help with dandruff and body odor?
A: ZLEY® UG is highly effective against Malassezia yeasts, the primary microorganisms associated with dandruff and seborrheic dermatitis. Additionally, its antimicrobial activity targets odor-causing bacteria, providing 24-hour deodorant efficacy by preventing the breakdown of sweat and sebum into malodorous compounds.
Q3: How does ZLEY® UG work as a preservation booster?
A: ZLEY® UG enhances the efficacy of traditional preservatives by disrupting microbial cell membranes, making microorganisms more susceptible to other preservative agents. This allows formulators to use lower concentrations of traditional preservatives (e.g., phenoxyethanol, parabens) while maintaining broad-spectrum protection. This is particularly valuable for sensitive skin and “clean beauty” formulations where reducing preservative load is a priority.
Q4: Is ZLEY® UG suitable for sensitive skin?
A: Yes. ZLEY® UG is derived from natural amino acid and fatty acid sources, making it mild and non-irritating. It is particularly well-suited for sensitive skin, baby care products, and gentle cleansers. Its preservation-boosting properties also allow formulators to reduce the concentration of potentially irritating traditional preservatives.
