ZLEY® Chlorhexidine Diacetate (CAS 56-95-1):
A Classic High-Efficiency Broad-Spectrum Disinfectant and Preservative
What is ZLEY®Chlorhexidine Diacetate?
Chlorhexidine Diacetate is a highly effective, broad-spectrum antimicrobial agent known for its strong efficacy and low toxicity. Its primary mechanism involves disrupting the cytoplasmic membrane of microorganisms, rapidly killing Gram-positive bacteria, Gram-negative bacteria, bacterial spores, fungi, and viruses.
ZLEY® is a professional supplier of Chlorhexidine Diacetate, delivering stable quality in compliance with major pharmacopoeia standards, expert technical support, and reliable global delivery to over 60 countries.
Product Specifications
| Property | Details |
| INCI Name | Chlorhexidine Diacetate |
| CAS Number | 56-95-1 |
| Appearance | White or almost white crystalline powder; odorless with a bitter taste |
| Recommended Usage | 0.02% – 0.05% |
| Solubility | Soluble in ethanol; slightly soluble in water |
| Key Functions | Preservative, disinfectant, antimicrobial agent |
Is ZLEY® Chlorhexidine Diacetate Safe?
Chlorhexidine Diacetate is safe when used within approved concentrations and applications. However, important considerations apply:
- Regulatory Compliance: Its use in cosmetics is strictly regulated. Limits vary by country (China, EU, US) regarding permitted product types and maximum concentrations. It is NOT permitted in leave-on skincare products.
- Approved Applications: Primarily used in professional disinfectants (hand/skin sanitizers, medical device disinfection), specific rinse-off products (antimicrobial body washes, dandruff shampoos), and medical materials.
- Avoid Contact: Keep away from sensitive areas such as eyes and middle ear. Some individuals may experience skin sensitivity.
Applications of ZLEY® Chlorhexidine Diacetate
Chlorhexidine Diacetate is a highly effective and safe external antimicrobial disinfectant. It effectively eliminates Staphylococcus aureus, Escherichia coli, and Candida albicans. As a cationic broad-spectrum antibacterial agent belonging to the bisbiguanide family, its mechanism involves disrupting the bacterial cell membrane. It serves as a disinfectant with potent bactericidal activity against Gram-positive bacteria, Gram-negative bacteria, and fungi, including Pseudomonas aeruginosa.
Common applications include skin disinfection, wound irrigation, and sterilization of surgical instruments.
Why Source from ZLEY?
With over 20 years of specialized experience, ZLEY understands both the science and the regulations governing antimicrobial ingredients. We provide:
High-quality Chlorhexidine Diacetate meeting USP, EP, and CP standards
Regulatory guidance for disinfectant product development
ormulation support to ensure safety, efficacy, and compliance in your target market
FAQs
Q1: How does Chlorhexidine Diacetate compare to other antimicrobials like Benzalkonium Chloride?
| Feature | Chlorhexidine Diacetate |
| Longer-lasting action | Forms a protective film on skin for prolonged antimicrobial effect |
| Broad-spectrum potency | Rapid and powerful action against bacteria and fungi |
| Better organic matter tolerance | Maintains activity even in the presence of small amounts of blood or pus |
Q2: What are the critical formulation considerations?
Regulatory First: Always verify that your target product type and market permit its use, and confirm the maximum allowed concentration.
Compatibility is Key: Avoid direct combination with anionic substances (soap, SLS) that can cause precipitation and inactivation. Always conduct thorough compatibility testing.
Proper Dissolution: Use correct solubilization techniques (hot water or pre-dissolving in alcohol) to ensure complete and stable incorporation.
Q3: How can I request samples, technical data, or a quotation?
Contact our international sales team at [email protected]
For a prompt and accurate response, please include:
- Your company information
- Target product type (e.g., hand sanitizer, surgical scrub)
- Target market(s) and country
We’ll provide tailored product recommendations, compliance-focused documentation, and competitive pricing.