ZLEY®BIOCARE-PHA – Hydroxyacetophenone (CAS 99-93-4):
Plant-Derived Green Preservation Synergist
Product Overview
ZLEY®BIOCARE-PHA (INCI: Hydroxyacetophenone) is a natural plant extract found in the stems and leaves of Artemisia capillaris (Asteraceae family), and the roots of Artemisia capillaris, Asclepiadaceae plants, and Ginseng vine..
Key Functions:
- Preservation synergist – Reduces or replaces traditional preservatives (e.g., Phenoxyethanol, Parabens) while enhancing overall antimicrobial efficacy
- Antifungal activity – Effective against fungi; requires combination with traditional preservatives for comprehensive protection
- Multifunctional benefits – Provides antioxidant, anti-irritant, emulsifying stabilization, and product protection properties
- Green preservative – Not listed in the official preservatives positive list, supporting “preservative-free” and “clean beauty” concepts
ZLEY® is a professional supplier of BIOCARE-PHA (CAS 99-93-4), providing stable quality, technical support, and global delivery covering over 60 countries. For specifications, samples, or quotations, please contact [email protected]
ZLEY®BIOCARE-PHA Product Information
| Parameter | Specification |
| INCI Name | Hydroxyacetophenone |
| CAS Number | 99-93-4 |
| Appearance | White to off-white crystals |
| Recommended Usage | 0.05 – 1.25% |
| Solubility | Easily soluble in hot water, methanol, ethanol, ether, acetone, benzene; slightly soluble in petroleum ether |
| Processing | Add directly to the formulation at room temperature and mix thoroughly |
Is ZLEY®BIOCARE-PHA Safe?
Yes. The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Hydroxyacetophenone as safe for use in cosmetics at concentrations up to 5.0%. Under normal, reasonable, and foreseeable conditions of use, it does not pose a risk to human health.
Product Applications
In cosmetics and skincare, ZLEY®BIOCARE-PHA functions primarily as a preservative. It is widely suitable for:
| Product Category | Examples |
| Skincare | Creams, masks, eye creams, serums |
| Hair Care | Shampoos, conditioners, cold waves, hair dyes, hair tonics |
| Personal Care | Soaps, shampoo bars |
| Other | Alkaline cosmetics, detergents |
Why Source ZLEY®BIOCARE-PHA from ZLEY®?
With over 20 years of integrated R&D, production, quality control, and sales experience, ZLEY® is committed to providing premium personal care raw materials and customized solutions. Our global delivery network serves customers in over 60 countries.
Email: [email protected]
What Technical Support Can You Expect?
- Formulation Support: Basic formulation recommendations, combination suggestions, and processing guidance
- Regulatory Consulting: Target market compliance assistance
- Quality Assurance: Consistent quality, competitive pricing, and reliable global logistics
- Market Intelligence: Latest trends and ingredient application insights
Frequently Asked Questions (FAQ)
Q1: Is ZLEY®BIOCARE-PHA a preservative?
A: No, it is not listed in the official cosmetic positive list of cosmetic preservatives. It functions as a green preservative booster that enhances antimicrobial efficacy while reducing or replacing traditional preservatives. This supports “preservative-free” and “clean beauty” formulations.
Q2: What is the recommended usage level?
A: The recommended usage range is 0.05–1.25%. Safety assessments confirm it is safe at concentrations up to 5.0%.
Q3: Does it work alone or with other preservatives?
A: It is effective against fungi but typically needs to be combined with traditional preservatives (such as Phenoxyethanol) for comprehensive broad-spectrum protection against bacteria, molds, and yeasts. This combination allows for reduced levels of traditional preservatives.
Q4: What are the additional benefits besides preservation?
A: ZLEY®BIOCARE-PHA also provides antioxidant, anti-irritant, and emulsion‑stabilizing benefits, making it a multifunctional additive that improves overall formulation performance.
Q5: What types of products is it suitable for?
A: It is suitable for a wide range for creams, masks, serums, shampoos, conditioners, soaps, and other skincare, hair care, and personal care products, including alkaline and detergent systems.