ZLEY® MecRetinol 10% (CAS 11103-57-4, 128446-33-3):
Advanced Cyclodextrin Molecular Encapsulation Technology – Maximizing Efficacy While Minimizing Irritation

Product Overview
ZLEY®MecRetinol10% is an innovative encapsulated retinol system composed of Retinol and Hydroxypropyl Cyclodextrin. This advanced delivery system utilizes cyclodextrin molecular encapsulation technology to overcome the inherent instability and irritation challenges associated with traditional retinol.
The technology leverages the unique hollow structure of hydroxypropyl-β-cyclodextrin, which features a hydrophobic inner cavity and a hydrophilic outer surface. Through molecular interactions such as Van der Waals forces and hydrogen bonding, retinol is precisely embedded within the internal hydrophobic space. This effectively “locks in” the retinol, forming a stable inclusion complex that significantly enhances retinol’s stability against light, heat, and oxidation while improving its bioavailability.
ZLEY® is a professional supplier of MecRetinol 10% (CAS 11103-57-4, 128446-33-3), providing stable quality, technical support, and global delivery services covering over 60 countries. For specifications, samples, or quotations,
please contact: [email protected]
ZLEY® MecRetinol 10% Product Information
| Parameter | Specification |
| INCI Name | Retinol, Hydroxypropyl Cyclodextrin |
| CAS Numbers | 11103-57-4, 128446-33-3 |
| Appearance | Pale yellow to yellow granular powder |
| Recommended Usage | 0.1 – 2.0% |
| Key Benefits | Anti-wrinkle, firming, brightening, acne improvement |
| Solubility | Soluble in alcohol |
| Processing | Avoid high temperatures. Dissolve in alcohol first, then add to the formulation below 50°C. |
Is ZLEY® MecRetinol 10% Safe?
ZLEY® MecRetinol 10% is considered safe for cosmetic use under normal, reasonable, and foreseeable conditions at the following recommended usage levels:
Leave-on products: Maximum concentration ≤ 2.1%
Rinse-off products: Maximum concentration ≤ 0.1%
Product Applications
In skincare formulations, ZLEY® MecRetinol 10% is primarily targeted at addressing:
Wrinkles and loss of firmness
Collagen production support
Acne and blemishes
Uneven skin tone
Product Benefits
When applied to the skin, ZLEY® MecRetinol 10% provides sustained, slow release of retinol. This controlled delivery mechanism results in:
Reduced irritation compared to free retinol
Enhanced efficacy for anti-wrinkle, brightening, and acne-fighting benefits
Improved stability throughout product shelf life
Why Source ZLEY® MecRetinol 10% from ZLEY®?
Through over 20 years of dedicated effort and pursuit of excellence, ZLEY® has evolved into a modern enterprise integrating research, production, quality control, and sales. We are committed to providing the highest quality personal care raw materials, semi-finished products, and customized formulation solutions. We strive to meet the diverse needs of our customers and ensure the delivery of superior products and service.
What Technical Support Can You Expect When Sourcing ZLEY® MecRetinol 10%?
As a specialized supplier, ZLEY® offers value that extends beyond the product itself:
Formulation Application Support: Provides basic formulation suggestions, combination recommendations, and processing guidance
Regulatory Consulting Services: Assists in interpreting regulatory requirements for target markets
Quality and Supply Assurance: Ensures consistent product quality, competitive pricing, and reliable global logistics delivery
Market Trend Information: Shares the latest market dynamics and ingredient application trends to support your product development strategy
ZLEY® MecRetinol 10%: Frequently Asked Questions (FAQ)
Q1:What is the recommended usage level and how should it be incorporated?
A: The recommended dosage is 0.1–2% in finished cosmetic formulations . ZLEY® MecRetinol 10% is soluble in alcohol . For optimal results, it should be dissolved in the alcohol phase of formulations. Its granular powder form and excellent emulsifying properties make it easy to incorporate into various product types including serums, creams, and anti-aging treatments
Q2: What does ZLEY® MecRetinol 10% look like and how stable is it?
A: It appears as a pale yellow to yellow granular powder. The cyclodextrin encapsulation provides “excellent resistance to oxidation” , which means it maintains potency longer than unprotected retinol during storage and throughout the product’s shelf life. It also offers strong emulsifying and lubricating properties that enhance formulation performance .
Q3: What types of products is ZLEY® MecRetinol 10% suitable for?
A: This ingredient is ideal for a wide range of anti-aging and skin-renewal skincare formulations , including:
- Anti-wrinkle serums and creams
- Night treatments and renewal creams
- Acne-management formulations
- Skin-smoothing and texture-refining products
Its enhanced stability makes it particularly valuable for formulations where traditional retinol might degrade too quickly.
