Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[2-(N-benzyl-N-methylamino)ethyl] ester hydrochloride
CAS No.: 111441-67-1
Molecular Formula: C₂₆H₂₉N₃O₆·HCl
Molecular Weight: 515.99 g/mol
Nicardipine Hydrochloride is a calcium channel blocker (CCB) widely used as an active pharmaceutical ingredient in cardiovascular therapy. It works by inhibiting calcium ion influx into vascular smooth muscle, resulting in vasodilation and reduced blood pressure. It is commonly formulated in oral capsules, injections, and extended-release tablets for the management of hypertension, angina pectoris, and other cardiac conditions.
Nicardipine Hydrochloride
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FAQs
What is nicardipine hydrochloride?
Nicardipine hydrochloride is the hydrochloride salt form of nicardipine, a calcium channel blocker belonging to the dihydropyridine class. It is primarily used in pharmaceutical applications for cardiovascular-related formulations.
What is nicardipine hydrochloride used for?
Nicardipine hydrochloride is used in pharmaceutical formulations to help manage blood pressure and support cardiovascular function. It is commonly formulated for clinical and hospital use under medical supervision.
Is nicardipine hydrochloride the same as nicardipine base?
No. Nicardipine hydrochloride is the salt form of nicardipine. The hydrochloride form improves stability and solubility, making it more suitable for pharmaceutical formulation and controlled dosing compared to the free base.
Is nicardipine hydrochloride water soluble?
Nicardipine hydrochloride shows improved solubility in water and polar solvents compared to nicardipine base, which is one reason the hydrochloride salt is commonly used in pharmaceutical products.
Is nicardipine hydrochloride safe for use?
Nicardipine hydrochloride is considered safe when used as prescribed and formulated in compliance with pharmaceutical regulations. Proper dosage, medical supervision, and regulatory compliance are essential to ensure safe and effective use.
What is nicardipine hydrochloride?
Nicardipine hydrochloride is the hydrochloride salt form of nicardipine, a calcium channel blocker belonging to the dihydropyridine class. It is primarily used in pharmaceutical applications for cardiovascular-related formulations.
What is nicardipine hydrochloride used for?
Nicardipine hydrochloride is used in pharmaceutical formulations to help manage blood pressure and support cardiovascular function. It is commonly formulated for clinical and hospital use under medical supervision.
Is nicardipine hydrochloride the same as nicardipine base?
No. Nicardipine hydrochloride is the salt form of nicardipine. The hydrochloride form improves stability and solubility, making it more suitable for pharmaceutical formulation and controlled dosing compared to the free base.
Is nicardipine hydrochloride water soluble?
Nicardipine hydrochloride shows improved solubility in water and polar solvents compared to nicardipine base, which is one reason the hydrochloride salt is commonly used in pharmaceutical products.
Is nicardipine hydrochloride safe for use?
Nicardipine hydrochloride is considered safe when used as prescribed and formulated in compliance with pharmaceutical regulations. Proper dosage, medical supervision, and regulatory compliance are essential to ensure safe and effective use.
Also Known As
Nicardipine hydrochloride
Nicardipine HCl
Nicardipine hydrochloride salt
(±)-Nicardipine hydrochloride
Nicardipine dihydrochloride
Nicardipine hydrochloride
Nicardipine HCl
Nicardipine hydrochloride salt
(±)-Nicardipine hydrochloride
Nicardipine dihydrochloride