Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[2-(N-benzyl-N-methylamino)ethyl] ester hydrochloride
CAS No.: 111441-67-1
Molecular Formula: C₂₆H₂₉N₃O₆·HCl
Molecular Weight: 515.99 g/mol
Nicardipine Hydrochloride is a calcium channel blocker (CCB) widely used as an active pharmaceutical ingredient in cardiovascular therapy. It works by inhibiting calcium ion influx into vascular smooth muscle, resulting in vasodilation and reduced blood pressure. It is commonly formulated in oral capsules, injections, and extended-release tablets for the management of hypertension, angina pectoris, and other cardiac conditions.
Nicardipine Hydrochloride
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What is nicardipine hydrochloride?
Nicardipine hydrochloride is the hydrochloride salt form of nicardipine, a calcium channel blocker belonging to the dihydropyridine class. It is primarily used in pharmaceutical applications for cardiovascular-related formulations.
What is nicardipine hydrochloride used for?
Nicardipine hydrochloride is used in pharmaceutical formulations to help manage blood pressure and support cardiovascular function. It is commonly formulated for clinical and hospital use under medical supervision.
Is nicardipine hydrochloride the same as nicardipine base?
No. Nicardipine hydrochloride is the salt form of nicardipine. The hydrochloride form improves stability and solubility, making it more suitable for pharmaceutical formulation and controlled dosing compared to the free base.
Is nicardipine hydrochloride water soluble?
Nicardipine hydrochloride shows improved solubility in water and polar solvents compared to nicardipine base, which is one reason the hydrochloride salt is commonly used in pharmaceutical products.
Is nicardipine hydrochloride safe for use?
Nicardipine hydrochloride is considered safe when used as prescribed and formulated in compliance with pharmaceutical regulations. Proper dosage, medical supervision, and regulatory compliance are essential to ensure safe and effective use.
Nicardipine hydrochloride
Nicardipine HCl
Nicardipine hydrochloride salt
(±)-Nicardipine hydrochloride
Nicardipine dihydrochloride
Nicardipine Hydrochloride at a glance
Nicardipine Hydrochloride is a ZLEY supplied material for professional formulation, R&D and procurement evaluation.
- INCI
- Not applicable — this page is categorized as an API rather than a cosmetic INCI ingredient
- CAS
- Not publicly specified — confirm against the current SDS/TDS
- Content / purity
- Grade-specific; confirm the current TDS specification and batch COA
- Appearance
- Confirm against the current TDS and batch COA
- Recommended dosage
- Not publicly specified — confirm intended use level and target-market requirements
- Solubility
- Not publicly specified — confirm with the current TDS and a formulation compatibility test
Formulation and purchasing details View 10 additional specifications
- Addition phase
- Not specified for a cosmetic formulation; consult the API specification and intended-use requirements
- Processing temperature
- Not publicly specified — confirm grade-specific processing limits in the current TDS
- pH
- Not publicly specified — confirm supplied-grade and finished-formula requirements
- Stability
- Validate compatibility, accelerated/real-time stability and final packaging in the finished formulation
- Storage
- Follow the current SDS/TDS and keep the material sealed under the stated storage conditions
- Shelf life
- Confirm against the current TDS and supplied batch documentation
- Applications
- API formulations; confirm finished-product fit and target-market requirements
- Packaging
- Pack size is grade/order specific; confirm on the current quotation and specification
- MOQ
- Available on request; confirm grade, pack size, lead time and destination with ZLEY sales
- TDS / SDS / COA
- TDS on request; SDS on request; Batch-specific COA available on request
Values marked for confirmation are intentionally not estimated. Request the current grade-specific TDS/SDS and batch COA before scale-up or purchase.
Technical documents
Product FAQ
What is Nicardipine Hydrochloride?
Nicardipine Hydrochloride is a ZLEY supplied material for professional formulation, R&D and procurement evaluation. The declared INCI is: Not applicable — this page is categorized as an API rather than a cosmetic INCI ingredient.
What is the recommended use level for Nicardipine Hydrochloride?
The published or currently recorded use level is Not publicly specified — confirm intended use level and target-market requirements. Final use level must be checked against the current TDS, the complete formula, target-market rules and finished-product testing.
How should Nicardipine Hydrochloride be incorporated?
Solubility: Not publicly specified — confirm with the current TDS and a formulation compatibility test. Addition phase: Not specified for a cosmetic formulation; consult the API specification and intended-use requirements. Processing temperature: Not publicly specified — confirm grade-specific processing limits in the current TDS.
Which technical and purchasing documents are available?
Request the current TDS; request the current SDS; request the batch-specific COA. Packaging and MOQ are order-specific and should be confirmed with ZLEY sales before purchase.
Technical review owner: ZLEY Group Technical Team Source review date: