CAS No.: 50-44-2
Molecular Formula: C₅H₄N₄S
Molecular Weight: 152.18 g/mol
Mercaptopurine, also known as 6-Mercaptopurine (6-MP), is a purine analog antimetabolite used as an active pharmaceutical ingredient in the treatment of acute lymphoblastic leukemia, chronic myeloid leukemia, and autoimmune disorders. It inhibits purine nucleotide synthesis, effectively suppressing abnormal cell proliferation.
Our Mercaptopurine is produced under strict GMP-compliant conditions, ensuring high purity, consistent quality, and reliable performance in formulation development and commercial manufacturing.
Quality Assurance
Produced under GMP-certified manufacturing facilities
Tested and released according to ICH Q7 and pharmacopoeial standards (USP/BP/EP)
Full documentation support: COA, MSDS, TDS, DMF (if applicable)
Mercaptopurine
IF YOU WANT SAMPLES
Please fill in the information
What is mercaptopurine?
Mercaptopurine is a purine analog that is primarily used as an immunosuppressive and chemotherapeutic agent. It interferes with DNA synthesis, making it effective in treating certain types of leukemia and autoimmune diseases.
What is mercaptopurine used for?
Mercaptopurine is used in the treatment of various types of leukemia, Crohn’s disease, and other autoimmune conditions. It works by suppressing the immune system to prevent abnormal cell growth and inflammation.
Is mercaptopurine the same as thioguanine?
No, mercaptopurine and thioguanine are both purine analogs, but they are different compounds. While both are used in chemotherapy and immune suppression, they differ in their chemical structure and specific therapeutic uses.
Is mercaptopurine safe for use?
Mercaptopurine is generally safe when prescribed and administered under medical supervision. However, it can cause side effects such as bone marrow suppression, liver toxicity, and increased susceptibility to infections, which require careful monitoring.
Can mercaptopurine be used in cancer treatment?
Yes, mercaptopurine is commonly used in the treatment of leukemia, particularly acute lymphoblastic leukemia (ALL), as part of combination chemotherapy regimens. It helps to inhibit the proliferation of cancerous cells.
Mercaptopurine
6-Mercaptopurine
6-MP
6-Thioguanine
Purine analog
Mercaptopurine at a glance
Mercaptopurine is a ZLEY supplied material for professional formulation, R&D and procurement evaluation.
- INCI
- Not applicable — this page is categorized as an API rather than a cosmetic INCI ingredient
- CAS
- Not publicly specified — confirm against the current SDS/TDS
- Content / purity
- Grade-specific; confirm the current TDS specification and batch COA
- Appearance
- Confirm against the current TDS and batch COA
- Recommended dosage
- Not publicly specified — confirm intended use level and target-market requirements
- Solubility
- Not publicly specified — confirm with the current TDS and a formulation compatibility test
Formulation and purchasing details View 10 additional specifications
- Addition phase
- Not specified for a cosmetic formulation; consult the API specification and intended-use requirements
- Processing temperature
- Not publicly specified — confirm grade-specific processing limits in the current TDS
- pH
- Not publicly specified — confirm supplied-grade and finished-formula requirements
- Stability
- Validate compatibility, accelerated/real-time stability and final packaging in the finished formulation
- Storage
- Follow the current SDS/TDS and keep the material sealed under the stated storage conditions
- Shelf life
- Confirm against the current TDS and supplied batch documentation
- Applications
- API formulations; confirm finished-product fit and target-market requirements
- Packaging
- Pack size is grade/order specific; confirm on the current quotation and specification
- MOQ
- Available on request; confirm grade, pack size, lead time and destination with ZLEY sales
- TDS / SDS / COA
- TDS on request; SDS on request; Batch-specific COA available on request
Values marked for confirmation are intentionally not estimated. Request the current grade-specific TDS/SDS and batch COA before scale-up or purchase.
Technical documents
Product FAQ
What is Mercaptopurine?
Mercaptopurine is a ZLEY supplied material for professional formulation, R&D and procurement evaluation. The declared INCI is: Not applicable — this page is categorized as an API rather than a cosmetic INCI ingredient.
What is the recommended use level for Mercaptopurine?
The published or currently recorded use level is Not publicly specified — confirm intended use level and target-market requirements. Final use level must be checked against the current TDS, the complete formula, target-market rules and finished-product testing.
How should Mercaptopurine be incorporated?
Solubility: Not publicly specified — confirm with the current TDS and a formulation compatibility test. Addition phase: Not specified for a cosmetic formulation; consult the API specification and intended-use requirements. Processing temperature: Not publicly specified — confirm grade-specific processing limits in the current TDS.
Which technical and purchasing documents are available?
Request the current TDS; request the current SDS; request the batch-specific COA. Packaging and MOQ are order-specific and should be confirmed with ZLEY sales before purchase.
Technical review owner: ZLEY Group Technical Team Source review date: